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Edible flowers - antioxidant activity and impact on cell viability

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dc.title Edible flowers - antioxidant activity and impact on cell viability en
dc.contributor.author Kuceková, Zdenka
dc.contributor.author Mlček, Jiří
dc.contributor.author Humpolíček, Petr
dc.contributor.author Rop, Otakar
dc.relation.ispartof Central European Journal of Biology
dc.identifier.issn 1895-104X OCLC, Ulrich, Sherpa/RoMEO, JCR
dc.date.issued 2013
utb.relation.volume 8
utb.relation.issue 10
dc.citation.spage 1023
dc.citation.epage 1031
dc.type article
dc.language.iso en
dc.publisher Versita en
dc.identifier.doi 10.2478/s11535-013-0212-y
dc.relation.uri http://link.springer.com/article/10.2478/s11535-013-0212-y
dc.subject Antioxidants en
dc.subject Cancer cells en
dc.subject Herbs en
dc.subject Polyphenols en
dc.description.abstract The phenolic compound composition, antioxidant activity and impact on cell viability of edible flower extracts of Allium schoenoprasum; Bellis perennis; Cichorium intybus; Rumex acetosa; Salvia pratensis; Sambucus nigra; Taraxacum officinale; Tragopogon pratensis; Trifolium repens and Viola arvensis was examined for the first time. Total phenolic content of the flowers of these plants fell between 11.72 and 42.74 mg of tannin equivalents/kg of dry matter. Antioxidant activity ranged from 35.56 to 71.62 g of ascorbic acid equivalents/kg of dry matter. Using the Human Hepatocellular Carcinoma cell-line (HepG2) and the Human Immortalized Non-tumorigenic Keratinocyte cell line (HaCaT), we assessed cell viability following a 3 day incubation period in media containing 25, 50, 75 and 100 μg/ml of total phenolic compounds using a colorimetric MTT assay. These three properties could make the herbs useful in treatment of various diseases like cancer. The tested extracts had significant effects on cell viability, but the effects were dependent not only on the phenolic compound concentration and the edible flowers species, but also on the phenolic compound and antioxidant profiles. In addition, responses differed between cell lines. © 2013 Versita Warsaw and Springer-Verlag Wien. en
utb.faculty Faculty of Technology
dc.identifier.uri http://hdl.handle.net/10563/1003440
utb.identifier.obdid 43869925
utb.identifier.scopus 2-s2.0-84881082319
utb.identifier.wok 000322674300010
utb.source j-scopus
dc.date.accessioned 2013-08-21T10:17:33Z
dc.date.available 2013-08-21T10:17:33Z
dc.rights Attribution-NonCommercial-NoDerivs 3.0 Unported
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/
dc.rights.access openAccess
utb.contributor.internalauthor Kuceková, Zdenka
utb.contributor.internalauthor Mlček, Jiří
utb.contributor.internalauthor Humpolíček, Petr
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