Health effects of grape seed and skin extracts and their influence on biochemical markers

Sochorová, Lenka; Průšová, Božena; Cebová, Martina; Juríková, Tünde; Mlček, Jiří; Adámková, Anna; Nedomová, Šárka; Baroň, Mojmír; Sochor, Jiří

dc.title	Health effects of grape seed and skin extracts and their influence on biochemical markers	en
dc.contributor.author	Sochorová, Lenka
dc.contributor.author	Průšová, Božena
dc.contributor.author	Cebová, Martina
dc.contributor.author	Juríková, Tünde
dc.contributor.author	Mlček, Jiří
dc.contributor.author	Adámková, Anna
dc.contributor.author	Nedomová, Šárka
dc.contributor.author	Baroň, Mojmír
dc.contributor.author	Sochor, Jiří
dc.relation.ispartof	Molecules
dc.identifier.issn	1420-3049 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued	2020
utb.relation.volume	25
utb.relation.issue	22
dc.type	review
dc.language.iso	en
dc.publisher	NLM (Medline)
dc.identifier.doi	10.3390/molecules25225311
dc.relation.uri	https://www.mdpi.com/1420-3049/25/22/5311
dc.subject	antioxidants	en
dc.subject	cancer	en
dc.subject	cardiovascular disease	en
dc.subject	diabetes mellitus	en
dc.subject	gastrointestinal tract	en
dc.subject	grape seeds	en
dc.subject	grape skin	en
dc.subject	neuroprotective effect	en
dc.description.abstract	This review is focused on the study of the effects of grape seed and skin extract (GSSE) on human health. GSSE contains high concentrations of important polyphenolic substances with high biological activity. This review is a summary of studies that investigate the effects of GSSE on diabetes mellitus, cardiovascular disease and cancer, its neuroprotective effect, and its effects on the gastrointestinal tract and other health complications related to these diseases. The results of the studies confirm that the anti-inflammatory, antiapoptotic, and pro-proliferative effects of "Vitis vinifera L." seed extract reduce the level of oxidative stress and improve the overall lipid metabolism.	en
utb.faculty	Faculty of Technology
dc.identifier.uri	http://hdl.handle.net/10563/1010061
utb.identifier.obdid	43881637
utb.identifier.scopus	2-s2.0-85096348962
utb.identifier.wok	000594119000001
utb.identifier.pubmed	33202575
utb.source	j-scopus
dc.date.accessioned	2020-12-09T01:52:47Z
dc.date.available	2020-12-09T01:52:47Z
dc.description.sponsorship	[IGA-ZF/2020-AP006]; [CZ.02.1.01/0.0/0.0/16_017/0002334]
dc.rights	Attribution 4.0 International
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/
dc.rights.access	openAccess
utb.ou	Department of Food Analysis and Chemistry
utb.contributor.internalauthor	Mlček, Jiří
utb.contributor.internalauthor	Adámková, Anna
utb.fulltext.affiliation	Lenka Sochorova 1, Bozena Prusova 1, Martina Cebova 2, Tunde Jurikova 3, Jiri Mlcek 4, Anna Adamkova 4, Sarka Nedomova 5, Mojmir Baron 1, Jiri Sochor 1* 1 Department of Viticulture and Enology, Faculty of Horticulture, Mendel University in Brno, Valtická 337, 691-44 Lednice, Czech Republic; tomaskova.l.9@gmail.com (L.S.); bozena.prusova@mendelu.cz (B.P.); MojmirBaron@seznam.cz (M.B.) 2 Centre of Experimental Medicine, Slovak Academy of Sciences, Institute of Normal and Pathological Physiology, 841-04 Bratislava, Slovakia; martina.cebova@savba.sk 3 Faculty of Central European Studies, Institute for Teacher Training, Constantine the Philosopher University in Nitra, Drazovska 4, SK-949-74 Nitra, Slovakia; tjurikova@ukf.sk 4 Department of Food Analysis and Chemistry, Faculty of Technology, Tomas Bata University in Zlin, Vavrečkova 275, 760-01 Zlin, Czech Republic; mlcek@utb.cz (J.M.); aadamkova@utb.cz (A.A.) 5 Department of Food Technology, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, 613-00 Brno, Czech Republic; sarka.nedomova@mendelu.cz * Correspondence: jiri.sochor@mendelu.cz; Tel.: +420-777-648-937
utb.fulltext.dates	Received: 15 October 2020 Accepted: 12 November 2020 Published: 14 November 2020
utb.fulltext.sponsorship	This work was supported by project IGA-ZF/2020-AP006 and by project CZ.02.1.01/0.0/0.0/16_017/0002334 Research Infrastructure for Young Scientists.
utb.wos.affiliation	[Sochorova, Lenka; Prusova, Bozena; Baron, Mojmir; Sochor, Jiri] Mendel Univ Brno, Dept Viticulture & Enol, Fac Hort, Valticka 337, Lednice 69144, Czech Republic; [Cebova, Martina] Slovak Acad Sci, Ctr Expt Med, Inst Normal & Pathol Physiol, Bratislava 84104, Slovakia; [Jurikova, Tunde] Constantine Philosopher Univ Nitra, Inst Teacher Training, Fac Cent European Studies, Drazovska 4, SK-94974 Nitra, Slovakia; [Mlcek, Jiri; Adamkova, Anna] Tomas Bata Univ Zlin, Dept Food Anal & Chem, Fac Technol, Vavreckova 275, Zlin 76001, Czech Republic; [Nedomova, Sarka] Mendel Univ Brno, Fac Agron, Dept Food Technol, Zemedelska 1, Brno 61300, Czech Republic
utb.scopus.affiliation	Department of Viticulture and Enology, Faculty of Horticulture, Mendel University in Brno, Valtická 337, Lednice, 691-44, Czech Republic; Centre of Experimental Medicine, Slovak Academy of Sciences, Institute of Normal and Pathological Physiology, Bratislava, 841-04, Slovakia; Faculty of Central European Studies, Institute for Teacher Training, Constantine the Philosopher University in Nitra, Drazovska 4, Nitra, SK-949-74, Slovakia; Department of Food Analysis and Chemistry, Faculty of Technology, Tomas Bata University in Zlin ,Vavrečkova 275Zlin 760-01, Czech Republic; Department of Food Technology, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, Brno, 613-00, Czech Republic
utb.fulltext.projects	IGA-ZF/2020-AP006
utb.fulltext.projects	CZ.02.1.01/0.0/0.0/16_017/0002334
utb.fulltext.faculty	Faculty of Technology
utb.fulltext.faculty	Faculty of Technology
utb.fulltext.ou	Department of Food Analysis and Chemistry
utb.fulltext.ou	Department of Food Analysis and Chemistry