Reaction of 1-substituted 3-aminoquinoline-2,4-diones with isothiocyanates. An easy pathway to generate novel 2-thioxo-10H-spiro[imidazoline-5,3-indole]-2,2´-diones.

Klásek, Antonín; Mrkvička, Vladimír; Mikšík, I.; Růžička, A.; Lyčka, Antonín

Title:

Author:

Klásek, Antonín; Mrkvička, Vladimír; Mikšík, I.; Růžička, A.; Lyčka, Antonín

Document type:

Peer-reviewed article (English)

Source document:

Tetrahedron. 2009, vol. 65, issue 25, p. 4908-4916

ISSN:

0040-4020 (Sherpa/RoMEO, JCR)

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DOI:

https://doi.org/10.1016/j.tet.2009.04.009

Abstract:

3-Butyl-3-aminoquinoline-2,4-diones react with isothiocyanates to give novel 3a-butyl-9b-hydroxy-hexahydro-imidazo[4,5-c]quinolin-2-ones . These compounds rearrange in an acidit environment to give (E)- and/or (Z)-4-butylidene-2-thioxo-1´H-spiro[imidazoline-5,3´-indole]-2,2-diones.

Full text:

https://www.sciencedirect.com/science/article/pii/S0040402009005237

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Citace článku v časopise:
KLÁSEK, Antonín, Vladimír MRKVIČKA, I. MIKŠÍK, A. RŮŽIČKA a Antonín LYČKA. Reaction of 1-substituted 3-aminoquinoline-2,4-diones with isothiocyanates. An easy pathway to generate novel 2-thioxo-10H-spiro[imidazoline-5,3-indole]-2,2´-diones. Tetrahedron [online]. 2009, vol. 65, iss. 25, s. 4908-4916. [cit. 2024-04-23]. ISSN 0040-4020. Dostupné z: https://www.sciencedirect.com/science/article/pii/S0040402009005237.

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