Preparation of 1-adamantyl ketones: Structure, mechanism of formation and biological activity of potential by-products

Vícha, Robert; Nečas, Marek; Potáček, Milan

Název:

Autor:

Vícha, Robert; Nečas, Marek; Potáček, Milan

Typ dokumentu:

Recenzovaný odborný článek (English)

Zdrojový dok.:

Collection of Czechoslovak Chemical Communications. 2006, vol. 71, issue 5, p. 709-722

ISSN:

0010-0765 (Sherpa/RoMEO, JCR)

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DOI:

https://doi.org/10.1135/cccc20060709

Abstrakt:

Reactions between adamantane-1-carbonyl chloride and several Grignard reagents as well as interactions with solvents have been examined. Some new and unexpected adamantane derivatives were isolated, fully characterized and their biological activity determined. In particular, an unexpected isochromanone 16 was formed in an SEAr process, in which a stable hydrocarbon was the leaving group.

Plný text:

http://cccc.uochb.cas.cz/71/5/0709/

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Citace článku v časopise:
VÍCHA, Robert, Marek NEČAS a Milan POTÁČEK. Preparation of 1-adamantyl ketones: Structure, mechanism of formation and biological activity of potential by-products. Collection of Czechoslovak Chemical Communications [online]. 2006, vol. 71, iss. 5, s. 709-722. [cit. 2024-04-19]. ISSN 0010-0765. Dostupné z: http://cccc.uochb.cas.cz/71/5/0709/.

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