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Mechanical strength, surface properties, cytocompatibility and antibacterial activity of nano zinc-magnesium silicate/polyetheretherketone biocomposites

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dc.title Mechanical strength, surface properties, cytocompatibility and antibacterial activity of nano zinc-magnesium silicate/polyetheretherketone biocomposites en
dc.contributor.author Tang, Xiaoming
dc.contributor.author Dai, Jian
dc.contributor.author Sun, Hailang
dc.contributor.author Saha, Nabanita
dc.contributor.author Sáha, Petr
dc.contributor.author Wang, Deqiang
dc.contributor.author Cheng, Qinlin
dc.contributor.author Wei, Jie
dc.relation.ispartof Journal of Nanoscience and Nanotechnology
dc.identifier.issn 1533-4880 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2019
utb.relation.volume 19
utb.relation.issue 12
dc.citation.spage 7615
dc.citation.epage 7623
dc.type article
dc.language.iso en
dc.publisher American Scientific Publishers
dc.identifier.doi 10.1166/jnn.2019.16727
dc.relation.uri https://www.ingentaconnect.com/content/asp/jnn/2019/00000019/00000012/art00015;jsessionid=g7gpfnp3a18qk.x-ic-live-03
dc.subject Polyetheretherketone en
dc.subject Nano Zinc-Magnesium Silicate en
dc.subject Cytocompatibility en
dc.subject Antibacterial Activity en
dc.description.abstract In order to improve the biological activity and antibacterial properties of polyetheretherketone (PK) as bone implants, nano zinc-magnesium silicate (nZMS)/PK bioactive composites (nZPC) were fabricated. The results revealed that the mechanical properties, surface roughness and hydrophilicity of the nZPC gradually increased with nZMS content, in which nZPC with 50 w% of nZMS (50nZPC) exhibited the best properties. In addition, incorporation of nZMS into PK significantly improved the apatite mineralization ability of nZPC, which depended on nZMS content. Moreover, the attachment, proliferation and differentiation of MC3T3-E1 cells on nZPC were significantly enhanced with increasing nZMS content. Furthermore, after incorporation of nZMS into PK, the nZPC could inhibit the growth of Escherichia coli (E. coli), in which 50nZPC revealed the best antibacterial activity. The results suggested that 50nZMPC with good bioactivity, cytocompatibility and antibacterial activity might be a promising candidate as an implant for bone repair and anti-infection. en
utb.faculty University Institute
dc.identifier.uri http://hdl.handle.net/10563/1008971
utb.identifier.wok 000473105800015
utb.identifier.pubmed 31196268
utb.source j-wok
dc.date.accessioned 2019-08-16T09:30:13Z
dc.date.available 2019-08-16T09:30:13Z
dc.description.sponsorship National Natural Science Foundation of China [51772194, 81771990]; Key Medical Program of Science and Technology Development of Shanghai [15441902500, 17441902000]; Ministry of Education, Youth and Sports of the Czech Republic-Program NPU I [LO1504]
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Saha, Nabanita
utb.contributor.internalauthor Sáha, Petr
utb.fulltext.sponsorship The grants were from the National Natural Science Foundation of China (51772194 and 81771990), Key Medical Program of Science and Technology Development of Shanghai (15441902500 and 17441902000) as well as by the Ministry of Education, Youth and Sports of the Czech Republic-Program NPU I (LO1504).
utb.wos.affiliation [Tang, Xiaoming; Dai, Jian; Sun, Hailang] Nanjing Med Univ, Affiliated Huaian Peoples Hosp 1, Dept Orthoped, Huaian 223300, Jiangsu, Peoples R China; [Nabanita, Saha; Petr, Saha] Tomas Bata Univ Zlin, Univ Inst, Ctr Polymer Syst, Tr T Bati 5678, Zlin 76001, Zlin, Czech Republic; [Wang, Deqiang; Cheng, Qinlin; Wei, Jie] East China Univ Sci & Technol, Minist Educ, Key Lab Ultrafine Mat, Shanghai 200237, Peoples R China
utb.fulltext.projects 51772194
utb.fulltext.projects 81771990
utb.fulltext.projects 15441902500
utb.fulltext.projects 17441902000
utb.fulltext.projects LO1504
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