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Hydration and barrier properties of emulsions with the addition of keratin hydrolysate

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dc.title Hydration and barrier properties of emulsions with the addition of keratin hydrolysate en
dc.contributor.author Mokrejš, Pavel
dc.contributor.author Pavlačková, Jana
dc.contributor.author Janáčová, Dagmar
dc.contributor.author Hut't'a, Matouš
dc.relation.ispartof Cosmetics
dc.identifier.issn 2079-9284 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2018
utb.relation.volume 5
utb.relation.issue 4
dc.type article
dc.language.iso en
dc.publisher MDPI
dc.identifier.doi 10.3390/cosmetics5040064
dc.relation.uri https://www.mdpi.com/2079-9284/5/4/64
dc.subject Emulsion en
dc.subject Humectant en
dc.subject Hydration en
dc.subject Keratin hydrolysate en
dc.subject Occlusive en
dc.subject Transepidermal water loss en
dc.description.abstract Although keratin hydrolysates (KH) are added to skin care agents, detailed studies on the moisturising effects of KH are lacking. The aim of this study is to test whether adding KH into an ointment base (OB) heighten hydration of the skin and diminish transepidermal loss of water (TEWL). Formulations containing 2%, 4%, and 6% of KH (based on OB weight) were prepared. Hydration, TEWL and skin pH were measured; intervals of measurements were as follows: 1, 2, 3, 4, 24 and 48 h. Testing was carried out on 10 men. In terms of hydration, supplementing the OB with 2% KH is optimal, as an 11-19% increase occurs in hydration of stratum corneum (SC). All the formulations with added KH as tested caused TEWL to decline after application. Keratin hydrolysate makes for an excellent occlusive; adding it to OB results in a 30-50% reduction in TEWL after application. KH functions as a humectant as well, as it helps to bind water from the lower layers of the epidermis to the SC. Formulations with additions of 2-6% of KH were stable in structure and did not cause phase separation even after 6 months storage. © 2018 by the authors. en
utb.faculty Faculty of Technology
utb.faculty Faculty of Applied Informatics
dc.identifier.uri http://hdl.handle.net/10563/1008365
utb.identifier.obdid 43878960
utb.identifier.scopus 2-s2.0-85058654819
utb.source j-scopus
dc.date.accessioned 2019-01-31T08:58:57Z
dc.date.available 2019-01-31T08:58:57Z
dc.rights Attribution 4.0 International
dc.rights.uri http://creativecommons.org/licenses/by/4.0/
dc.rights.access openAccess
utb.contributor.internalauthor Mokrejš, Pavel
utb.contributor.internalauthor Pavlačková, Jana
utb.contributor.internalauthor Janáčová, Dagmar
utb.contributor.internalauthor Hut't'a, Matouš
utb.fulltext.affiliation Pavel Mokrejš 1*, Jana Pavlačková 2, Dagmar Janáčová 3, Matouš Hut’t’a 1 1 Department of Polymer Engineering, Faculty of Technology, Tomas Bata University in Zlín, Vavrečkova 275, 760 01 Zlín, Czech Republic; h.matte@seznam.cz 2 Department of Fat, Tenside and Cosmetics Technology, Faculty of Technology, Tomas Bata University in Zlín, Vavrečkova 275, 760 01 Zlín, Czech Republic; pavlackova@utb.cz 3 Department of Processing Control and Applied Computer Science, Faculty of Applied Informatics, Tomas Bata University in Zlín, Nad Stráněmi 4511, 760 05 Zlín, Czech Republic; janacova@utb.cz * Correspondence: mokrejs@utb.cz or mokrejs@ft.utb.cz; Tel.: +420-576-031-230
utb.fulltext.dates Received: 6 September 2018 Accepted: 29 October 2018 Published: 31 October 2018
utb.scopus.affiliation Department of Polymer Engineering, Faculty of Technology, Tomas Bata University in Zlín, Vavrečkova 275, Zlín, 760 01, Czech Republic; Department of Fat, Tenside and Cosmetics Technology, Faculty of Technology, Tomas Bata University in Zlín, Vavrečkova 275, Zlín, 760 01, Czech Republic; Department of Processing Control and Applied Computer Science, Faculty of Applied Informatics, Tomas Bata University in Zlín, Nad Stráněmi 4511, Zlín, 760 05, Czech Republic
utb.fulltext.faculty Faculty of Technology
utb.fulltext.faculty Faculty of Technology
utb.fulltext.faculty Faculty of Applied Informatics
utb.fulltext.faculty Faculty of Technology
utb.fulltext.ou Department of Polymer Engineering
utb.fulltext.ou Department of Fat, Tenside and Cosmetics Technology
utb.fulltext.ou Department of Processing Control and Applied Computer Science
utb.fulltext.ou Department of Polymer Engineering
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