TBU Publications
Repository of TBU Publications

Vitamin D supplementation in inflammatory bowel disease: the role of dosage and patient compliance

DSpace Repository

Show simple item record

dc.title Vitamin D supplementation in inflammatory bowel disease: the role of dosage and patient compliance en
dc.contributor.author Kojecký, Vladimír
dc.contributor.author Adamíková, Alena
dc.contributor.author Klímek, Petr
dc.relation.ispartof Bratislava Medical Journal-Bratislavske Lekarske Listy
dc.identifier.issn 0006-9248 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2016
utb.relation.volume 117
utb.relation.issue 3
dc.citation.spage 148
dc.citation.epage 151
dc.type article
dc.language.iso en
dc.publisher Comenius Univ
dc.identifier.doi 10.4149/BLL_2016_028
dc.subject inflammatory bowel disease en
dc.subject vitamin D en
dc.subject supplementation en
dc.subject Crohn's disease en
dc.description.abstract OBJECTIVES: Vitamin D substitution is recommended in patients with inflammatory bowel disease. Specific guidelines are lacking. The aim of this study was to assess the effect of vitamin D supplementation with respect to dosage and patient compliance. METHODS: A prospective cohort study of 167 Crohn disease/ulcerative colitis outpatients. Patients were screened for serum vitamin D (250HD(2+3)) at the end of summer and in late winter. Demographic data, history of vitamin D supplementation were recorded and matched with prescription records. RESULTS: A total of 57 subjects used vitamin D supplementation (mean dose 1104 IU/day). 250HD(2+3) levels were lower (p < 0.001) in winter both in substituted and unsubstituted group, without any differences between groups within the same season. 250HD(2+3) levels did not correlate with the substitution dose. 52.1 % of subjects were fully compliant with substitution. 250HD(2+3) and prevalence of vitamin D deficit in this group were comparable with unsubstituted subjects except a higher prevalence of vitamin D insufficiency (p < 0.02). CONCLUSION: Fixed dosage of 1100 IU/day of vitamin D was insufficient to correct the deficiency. Patient compliance with vitamin D supplementation was low, however this fact did not significantly contribute to the degree of vitamin D deficiency in this dosage (Tab. 3, Fig. 1, Ref. 21). Text in PDF www.elis.sk. en
utb.faculty Faculty of Management and Economics
dc.identifier.uri http://hdl.handle.net/10563/1006348
utb.identifier.obdid 43875087
utb.identifier.scopus 2-s2.0-85014966556
utb.identifier.wok 000371851500005
utb.identifier.pubmed 26925744
utb.source j-wok
dc.date.accessioned 2016-06-22T12:14:50Z
dc.date.available 2016-06-22T12:14:50Z
utb.contributor.internalauthor Klímek, Petr
utb.fulltext.affiliation Kojecky V 1, Adamikova A 1, Klimek P 2 Internal Clinic, Bata Regional Hospital, Zlin, Czech Republic. kojecky@bnzlin.cz 1 Internal Clinic, Bata Regional Hospital, Zlin, 2 Department of Statistics and Quantitative Methods, Faculty of Management and Economics, Tomas Bata University in Zlín, Czech Republic Address for correspondence: V. Kojecky, Internal Clinic, Bata Regional Hospital Zlin, Havl. nab. 600, CZ- 760 01 Zlin, Czech Republic Phone: +420577552512, Fax: +420577552755
utb.fulltext.dates Received June 7, 2015 Accepted October 27, 2015
utb.fulltext.faculty Faculty of Management and Economics
utb.fulltext.ou Department of Statistics and Quantitative Methods
Find Full text

Files in this item

Show simple item record