TBU Publications
Repository of TBU Publications

Viscoelastic and mechanical properties of hyaluronan films and hydrogels modified by carbodiimide

DSpace Repository

Show simple item record

dc.title Viscoelastic and mechanical properties of hyaluronan films and hydrogels modified by carbodiimide en
dc.contributor.author Gřundělová, Lenka
dc.contributor.author Gregorová, Adriana
dc.contributor.author Mráček, Aleš
dc.contributor.author Vícha, Robert
dc.contributor.author Smolka, Petr
dc.contributor.author Minařík, Antonín
dc.relation.ispartof Carbohydrate Polymers
dc.identifier.issn 0144-8617 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2015
utb.relation.volume 119
dc.citation.spage 142
dc.citation.epage 148
dc.type article
dc.language.iso en
dc.publisher Pergamon Elsevier Science Ltd.
dc.identifier.doi 10.1016/j.carbpol.2014.11.049
dc.relation.uri https://www.sciencedirect.com/science/article/pii/S014486171401162X
dc.subject Carbodiimide en
dc.subject Hyaluronan en
dc.subject Mechanical properties en
dc.subject Modification en
dc.subject Viscoelastic properties en
dc.description.abstract This study investigated an effect of different ways of the preparation of insoluble hyaluronan material on its mechanical and viscoelastic properties. Hyaluronan (NaHy) of molecular weight Mw = 500,000 g mol-1 was modified with N-(3-dimethylaminopropyl-N′-ethylcarbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS), to be able absorb liquid without changing its mechanical properties. The modified, water insoluble NaHy materials were prepared in different geometry; as modified films and modified cylinders with exact dimensions. The occurrence of modification was confirmed by FT-IR (Fourier transform infrared spectroscopy) and 1H NMR (proton nuclear magnetic resonance) spectroscopy and swelling test. The determined mechanical and viscoelastic properties of unmodified and modified hyaluronan revealed the high dependency of elasticity changes depending on the gel processing method. Moreover, NaHy gels in the cylindrical form with the sponge-like structure predominant them as a convenient geometry for application in a humid environment. en
utb.faculty Faculty of Technology
utb.faculty University Institute
dc.identifier.uri http://hdl.handle.net/10563/1004102
utb.identifier.rivid RIV/70883521:28610/15:43872974!RIV16-MSM-28610___
utb.identifier.obdid 43873394
utb.identifier.scopus 2-s2.0-84916897060
utb.identifier.wok 000348953700017
utb.identifier.coden CAPOD
utb.source j-scopus
dc.date.accessioned 2015-01-29T11:34:31Z
dc.date.available 2015-01-29T11:34:31Z
dc.description.sponsorship Operational Program Research and Development Fund (ERDF); national budget of Czech Republic, within the framework of project Centre of Polymer Systems [CZ.1.05/2.1.00/03.0111]; TBU in Zlin [IGA/FT/2013/015, IGA/FT/2014/018]; national budget of Czech Republic; Graz University of Technology [F-AF-2-638-01]
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Gřundělová, Lenka
utb.contributor.internalauthor Mráček, Aleš
utb.contributor.internalauthor Vícha, Robert
utb.contributor.internalauthor Smolka, Petr
utb.contributor.internalauthor Minařík, Antonín
Find Full text

Files in this item

Show simple item record