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Polyphenolic extracts of edible flowers incorporated onto atelocollagen matrices and their effect on cell viability

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dc.title Polyphenolic extracts of edible flowers incorporated onto atelocollagen matrices and their effect on cell viability en
dc.contributor.author López García, Jorge Andrés
dc.contributor.author Kuceková, Zdenka
dc.contributor.author Humpolíček, Petr
dc.contributor.author Mlček, Jiří
dc.contributor.author Sáha, Petr
dc.relation.ispartof Molecules
dc.identifier.issn 1420-3049 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2013
utb.relation.volume 18
utb.relation.issue 11
dc.citation.spage 13435
dc.citation.epage 13445
dc.type article
dc.language.iso en
dc.publisher MDPI AG en
dc.identifier.doi 10.3390/molecules181113435
dc.relation.uri http://www.mdpi.com/1420-3049/18/11/13435
dc.subject Atelocollagen thin films en
dc.subject Cell viability en
dc.subject Edible flowers en
dc.subject Polyphenolic extracts en
dc.subject Tissue engineering en
dc.description.abstract The phenolic extract of chives flowers (Allium schoenoprasum, Liliaceae), introduced Sage (Salvia pratensis, Lamiaceae), European elderberry (Sambucus nigra, Caprifoliaceae) and common dandelion (Taraxacum officinale, Asteraceae) were characterised by High Performance Liquid Chromatography and incorporated in different concentrations onto atelocollagen thin films. In order to assess the biological impact of these phenolic compounds on cell viability, human immortalised non-tumorigenic keratinocyte cell line was seeded on the thin films and cell proliferation was determined by using an MTT assay. In addition, their antimicrobial activity was estimated by using an agar diffusion test. Data indicated the concomitance between cell viability and concentration of polyphenols. These findings suggest that these phenolic-endowed atelocollagen films might be suitable for tissue engineering applications, on account of the combined activity of polyphenols and collagen. © 2013 by the authors. en
utb.faculty University Institute
dc.identifier.uri http://hdl.handle.net/10563/1003574
utb.identifier.obdid 43870233
utb.identifier.scopus 2-s2.0-84888587167
utb.identifier.wok 000330311500023
utb.identifier.coden MOLEF
utb.source j-scopus
dc.date.accessioned 2013-12-18T16:07:41Z
dc.date.available 2013-12-18T16:07:41Z
dc.description.sponsorship European Regional Development Fund (ERDF); project Centre of Polymer Systems [CZ.1.05/2.1.00/03.0111]; Advanced Theoretical and Experimental Studies of Polymer Systems [CZ.1.07/2.3.00/20.0104]; Czech Science Foundation [13-08944S]; TBU in Zlin [IGA/FT/2013/019]
dc.rights Attribution-NonCommercial-NoDerivs 3.0 Unported
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/3.0/
dc.rights.access openAccess
utb.contributor.internalauthor López García, Jorge Andrés
utb.contributor.internalauthor Kuceková, Zdenka
utb.contributor.internalauthor Humpolíček, Petr
utb.contributor.internalauthor Mlček, Jiří
utb.contributor.internalauthor Sáha, Petr
utb.fulltext.affiliation Jorge López-García 1, Zdenka Kuceková 1,2, Petr Humpolíček 1,2,*, Jiři Mlček 3 and Petr Sáha 1 1 Centre of Polymer Systems, Tomas Bata University in Zlín, nám. T.G.Masaryka-5555, Zlín 76001, Czech Republic; E-Mails: vextropk@gmail.com (J.L.-G.); kucekova@ft.utb.cz (Z.K.); saha@utb.cz (P.S.) 2 Polymer Centre, Faculty of Technology, Tomas Bata University in Zlin, T.G.M. sq. 275, Zlin 76272, Czech Republic 3 Department of Food Analysis and Chemistry, Faculty of Technology, Tomas Bata University in Zlin, nám. T.G.Masaryka-5555, Zlin 76272, Czech Republic; E-Mail: mlcek@ft.utb.cz * Author to whom any correspondence should be addressed; E-Mail: humpolicek@ft.utb.cz; Tel.: +420-73-479-2298; Fax: +420-57-603-1444.
utb.fulltext.dates Received: 30 August 2013; in revised form: 3 October 2013 / Accepted: 23 October 2013 / Published: 30 October 2013
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utb.fulltext.sponsorship The authors would like to express their gratitude to the Operational Program Research and Development for Innovations co-funded by the European Regional Development Fund (ERDF) and national budget of Czech Republic, within the framework of project Centre of Polymer Systems (reg. number: CZ.1.05/2.1.00/03.0111), the Advanced Theoretical and Experimental Studies of Polymer Systems (reg. number: CZ.1.07/2.3.00/20.0104) and the Czech Science Foundation (13-08944S). Zdenka Kuceková would also like to thank the internal grant of TBU in Zlin No. IGA/FT/2013/019 funded for her financial support.
utb.fulltext.projects CZ.1.05/2.1.00/03.0111
utb.fulltext.projects CZ.1.07/2.3.00/20.0104
utb.fulltext.projects 13-08944S
utb.fulltext.projects IGA/FT/2013/019
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Attribution-NonCommercial-NoDerivs 3.0 Unported Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Unported