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Novel route to 4-(adamantan-1-yl)quinoline derivatives based on the Friedländer condensation

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dc.title Novel route to 4-(adamantan-1-yl)quinoline derivatives based on the Friedländer condensation en
dc.contributor.author Kozubková, Zuzana
dc.contributor.author Rouchal, Michal
dc.contributor.author Nečas, Marek
dc.contributor.author Vícha, Robert
dc.relation.ispartof Helvetica Chimica Acta
dc.identifier.issn 0018-019X Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2012
utb.relation.volume 95
utb.relation.issue 6
dc.citation.spage 1003
dc.citation.epage 1017
dc.type article
dc.language.iso en
dc.publisher Verlag Helvetica Chimica Acta AG en
dc.identifier.doi 10.1002/hlca.201100432
dc.relation.uri http://onlinelibrary.wiley.com/doi/10.1002/hlca.201100432/abstract
dc.description.abstract 2,3,4-Trisubstituted quinolines, substituted with adamantan-1-yl or (adamantan-1-yl)methyl in the 4-position, were prepared from the corresponding admantan-1-yl 2-aminophenyl ketones or admantan-1-ylmethyl 2-aminophenyl ketones and ketones with an α-CH2 group. These reactions were carried out under neat conditions or in toluene, and the products were obtained in moderate-to-excellent yields. The scope and limitations of the examined procedures are discussed. All new compounds are fully characterized by IR and NMRspectroscopy and mass spectrometry. The molecular structures of five new quinolines, obtained via single-crystal X-ray diffraction analyses, are discussed. © 2012 Verlag Helvetica Chimica Acta AG. en
utb.faculty Faculty of Technology
dc.identifier.uri http://hdl.handle.net/10563/1002885
utb.identifier.rivid RIV/70883521:28110/12:43867998!RIV13-MSM-28110___
utb.identifier.obdid 43868089
utb.identifier.scopus 2-s2.0-84862547251
utb.identifier.wok 000305295200016
utb.identifier.coden HCACA
utb.source j-scopus
dc.date.accessioned 2012-07-11T11:41:51Z
dc.date.available 2012-07-11T11:41:51Z
utb.contributor.internalauthor Kozubková, Zuzana
utb.contributor.internalauthor Rouchal, Michal
utb.contributor.internalauthor Vícha, Robert
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