Preparation of 1-adamantyl ketones: Structure, mechanism of formation and biological activity of potential by-products

Vícha, Robert; Nečas, Marek; Potáček, Milan

dc.title	Preparation of 1-adamantyl ketones: Structure, mechanism of formation and biological activity of potential by-products	en
dc.contributor.author	Vícha, Robert
dc.contributor.author	Nečas, Marek
dc.contributor.author	Potáček, Milan
dc.relation.ispartof	Collection of Czechoslovak Chemical Communications
dc.identifier.issn	0010-0765 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued	2006
utb.relation.volume	71
utb.relation.issue	5
dc.citation.spage	709
dc.citation.epage	722
dc.type	article
dc.language.iso	en
dc.publisher	Ústav organické chemie a biochemie Akademie věd České republiky (ÚOCHB)	cs
dc.identifier.doi	10.1135/cccc20060709
dc.relation.uri	http://cccc.uochb.cas.cz/71/5/0709/
dc.subject	adamantane	en
dc.subject	1-adamantyl alkyl/aryl ketones	en
dc.subject	acyl chlorides	en
dc.subject	side products	en
dc.subject	biological activity	en
dc.subject	Grignard reagents	en
dc.description.abstract	Reactions between adamantane-1-carbonyl chloride and several Grignard reagents as well as interactions with solvents have been examined. Some new and unexpected adamantane derivatives were isolated, fully characterized and their biological activity determined. In particular, an unexpected isochromanone 16 was formed in an SEAr process, in which a stable hydrocarbon was the leaving group.	en
utb.faculty	Faculty of Technology
dc.identifier.uri	http://hdl.handle.net/10563/1002076
utb.identifier.obdid	14555745
utb.identifier.scopus	2-s2.0-33745511191
utb.identifier.wok	000238419400008
utb.identifier.coden	CCCCA
utb.source	j-wok
dc.date.accessioned	2011-08-16T15:06:25Z
dc.date.available	2011-08-16T15:06:25Z
utb.contributor.internalauthor	Vícha, Robert