TBU Publications
Repository of TBU Publications

Development and characterization of novel medicated hydrogels for wound dressing

DSpace Repository

Show simple item record

dc.title Development and characterization of novel medicated hydrogels for wound dressing en
dc.contributor.author Roy, Niladri
dc.contributor.author Saha, Nabanita
dc.contributor.author Kitano, Takeshi
dc.contributor.author Sáha, Petr
dc.relation.ispartof Soft Materials
dc.identifier.issn 1539-445X Scopus Sources, Sherpa/RoMEO, JCR
dc.identifier.issn 1539-4468 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2010
utb.relation.volume 8
utb.relation.issue 2
dc.citation.spage 130
dc.citation.epage 148
dc.type article
dc.language.iso en
dc.publisher Royal Society of Chemistry (RSC) en
dc.identifier.doi 10.1080/15394451003756282
dc.relation.uri http://www.informaworld.com/smpp/content~db=all?content=10.1080/15394451003756282
dc.subject kyselina boritá cs
dc.subject hydrogel cs
dc.subject krytí ran cs
dc.subject visko-elastické vlastnosti cs
dc.subject botnání cs
dc.subject Boric acid en
dc.subject hydrogels en
dc.subject swell en
dc.description.abstract Hydrogely s léčivým účinkem byly asepticky připraveny z polyvinyl pyrolidonu, sodné soli karboxymetylcelulozy a polyetylénglykolu, agaru, glycerolu a/nebo kyseliny borité. Hydrogely byly charakterizovány pomocí optické mikroskopie, botnací studie, infračervené spektroskopie, skenovací elektronové mikroskopie a reologických měření. Výsledky ukazují, že připravené hydrogely mají sílné antimikrobní vlastnosti. cs
dc.description.abstract The medicated hydrogels were prepared aseptically under moist heat treatment using polyvinylpyrrolidone (PVP), sodium-carboxymethylcellulose (CMC), polyethyleneglycol (PEG), agar, glycerin and/or boric acid (BA) and designated as PVP-CMC and PVP-CMC-BA. The aim of this study was to develop some medicinal values-based hydrogels. BA was used to build up the medicinal values (antiseptic and antimicrobial properties) within the hydrogels. Optical images, scanning electron microscopy (SEM), and Fourier transform infrared (FTIR) spectroscopy of the hydrogels indicated that boric acid is uniformly dispersed within the cross-linked hydrogel network that may heal and protect the wounds from infections/sepsis. Swelling study in presence of water and physiological saline solution confirmed its reasonable absorption capacity. The rheological properties and mechanical properties demonstrated that the boric acid incorporated hydrogels are quite flexible. Assessment of antimicrobial property study proves that PVP-CMC-BA (3% BA) has strong infection protection capacity. en
utb.faculty Faculty of Technology
dc.identifier.uri http://hdl.handle.net/10563/1001207
utb.identifier.rivid RIV/70883521:28110/10:63509501!RIV11-MSM-28110___
utb.identifier.obdid 43864565
utb.identifier.scopus 2-s2.0-77953854735
utb.identifier.wok 000281359400006
utb.source j-riv
dc.rights.access openAccess
utb.contributor.internalauthor Roy, Niladri
utb.contributor.internalauthor Saha, Nabanita
utb.contributor.internalauthor Kitano, Takeshi
utb.contributor.internalauthor Sáha, Petr
Find Full text

Files in this item

Show simple item record