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Stem cell differentiation on conducting polyaniline

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dc.title Stem cell differentiation on conducting polyaniline en
dc.contributor.author Humpolíček, Petr
dc.contributor.author Radaszkiewicz, Katarzyna Anna
dc.contributor.author Kašpárková, Věra
dc.contributor.author Stejskal, Jaroslav
dc.contributor.author Trchová, Miroslava
dc.contributor.author Kuceková, Zdenka
dc.contributor.author Vičarová, H.
dc.contributor.author Pacherník, Jiří
dc.contributor.author Lehocký, Marián
dc.contributor.author Minařík, Antonín
dc.relation.ispartof RSC Advances
dc.identifier.issn 2046-2069 OCLC, Ulrich, Sherpa/RoMEO, JCR
dc.date.issued 2015
utb.relation.volume 5
utb.relation.issue 84
dc.citation.spage 68796
dc.citation.epage 68805
dc.type article
dc.language.iso en
dc.publisher Royal Society of Chemistry (RSC)
dc.identifier.doi 10.1039/c5ra12218j
dc.relation.uri http://pubs.rsc.org/en/Content/ArticleLanding/2015/RA/C5RA12218J#!divAbstract
dc.description.abstract Polyaniline is a promising conducting polymer with broad application potential in biomedicine. Its medical use, however, requires both biocompatibility and suitable physico-chemical and surface properties. The microstructure, electrical properties, and surface characteristics of polyaniline salt, polyaniline base, and polyaniline deposited with biologically active poly(2-acrylamido-2-methyl-1-propanesulfonic acid) were revealed using atomic force microscopy, contact angle measurements, and Raman spectroscopy. As conducting polymers can be preferentially applied in tissue engineering of heart and nervous tissues, the cardiomyogenesis in pure cardiomyocytes derived from embryonic stem cells and neurogenesis in neural progenitors isolated from embryonal 13 dpc brain were further investigated. The results show that neither cardiomyogenesis nor neurogenesis were influenced by any of the tested polyaniline films. However, the most favorable cell behaviour was observed on pristine polyaniline base; therefore, polyaniline in pristine forms without any further modification can be applied in a variety of biomedical fields. © The Royal Society of Chemistry 2015. en
utb.faculty Faculty of Technology
utb.faculty University Institute
dc.identifier.uri http://hdl.handle.net/10563/1005288
utb.identifier.rivid RIV/70883521:28610/15:43873010!RIV16-MSM-28610___
utb.identifier.obdid 43873430
utb.identifier.scopus 2-s2.0-84939511476
utb.identifier.wok 000359568400070
utb.identifier.coden RSCAC
utb.source j-wok
dc.date.accessioned 2015-09-09T15:16:27Z
dc.date.available 2015-09-09T15:16:27Z
dc.description.sponsorship 13-08944S, GACR, Czech Science Foundation
dc.description.sponsorship Czech Science Foundation [13-08944S]; Ministry of Education, Youth and Sports of the Czech Republic - Program NPU I [LO1504]
dc.rights Attribution 3.0 International
dc.rights.uri http://creativecommons.org/licenses/by/3.0/
dc.rights.access openAccess
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Humpolíček, Petr
utb.contributor.internalauthor Kašpárková, Věra
utb.contributor.internalauthor Kuceková, Zdenka
utb.contributor.internalauthor Lehocký, Marián
utb.contributor.internalauthor Minařík, Antonín
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