Reaction of 1-substituted 3-aminoquinoline-2,4-diones with isothiocyanates. An easy pathway to generate novel 2-thioxo-10H-spiro[imidazoline-5,3-indole]-2,2´-diones.

Klásek, Antonín; Mrkvička, Vladimír; Mikšík, I.; Růžička, A.; Lyčka, Antonín

dc.title	Reaction of 1-substituted 3-aminoquinoline-2,4-diones with isothiocyanates. An easy pathway to generate novel 2-thioxo-10H-spiro[imidazoline-5,3-indole]-2,2´-diones.	en
dc.contributor.author	Klásek, Antonín
dc.contributor.author	Mrkvička, Vladimír
dc.contributor.author	Mikšík, I.
dc.contributor.author	Růžička, A.
dc.contributor.author	Lyčka, Antonín
dc.relation.ispartof	Tetrahedron
dc.identifier.issn	0040-4020 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued	2009
utb.relation.volume	65
utb.relation.issue	25
dc.citation.spage	4908
dc.citation.epage	4916
dc.type	article
dc.language.iso	en
dc.publisher	Pergamon Elsevier Science Ltd.	en
dc.identifier.doi	10.1016/j.tet.2009.04.009
dc.relation.uri	https://www.sciencedirect.com/science/article/pii/S0040402009005237
dc.subject	Enamides	en
dc.subject	Rearrangement	en
dc.subject	Thiourea derivatives	en
dc.subject	Spiro-heterocycles	en
dc.subject	α-Aminoketones	en
dc.description.abstract	3-Butyl-3-aminochinolin-2,4-diony reagují s isothiokyanáty za tvorby nových 3a-butyl-9b-hydroxy-hexahydro-imidazo[4,5-c]chinolin-2-onů. Tyto sloučeniny přesmykují v kyselém prostředí a poskytují (E)- a/nebo (Z)-4-butyliden-2-thioxo-1´H-spiro[imidazolin-5,3´-indol]-2,2-diony.	cs
dc.description.abstract	3-Butyl-3-aminoquinoline-2,4-diones react with isothiocyanates to give novel 3a-butyl-9b-hydroxy-hexahydro-imidazo[4,5-c]quinolin-2-ones . These compounds rearrange in an acidit environment to give (E)- and/or (Z)-4-butylidene-2-thioxo-1´H-spiro[imidazoline-5,3´-indole]-2,2-diones.	en
utb.faculty	Faculty of Technology
dc.identifier.uri	http://hdl.handle.net/10563/1000991
utb.identifier.rivid	RIV/70883521:28110/09:63508077!RIV10-MSM-28110___
utb.identifier.obdid	43860113
utb.identifier.scopus	2-s2.0-65549140188
utb.identifier.wok	000267009400019
utb.source	j-riv
utb.contributor.internalauthor	Klásek, Antonín
utb.contributor.internalauthor	Mrkvička, Vladimír
utb.scopus.affiliation	Klásek A., Department of Chemistry, Faculty of Technology, Tomas Bata University, 762 72 Zlín, Czech Republic; Mrkvička V., Department of Chemistry, Faculty of Technology, Tomas Bata University, 762 72 Zlín, Czech Republic; Lyčka A., Research Institute for Organic Syntheses (VUOS), 533 54 Pardubice 20, Rybitví 296, Czech Republic, University of Hradec Králové, Faculty of Education, CZ 500 03 Hradec Kralove 3, Rokitanského 62, Czech Republic; Mikšík I., University of Hradec Králové, Faculty of Education, CZ 500 03 Hradec Kralove 3, Rokitanského 62, Czech Republic, Institute of Physiology, the Academy of Sciences of the Czech Republic, 142 20 Prague, Czech Republic; Růžička A., Department of General and Inorganic Chemistry, Faculty of Chemical Technology, University of Pardubice, 53210 Pardubice, Czech Republic