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Hodnocení stability n-alkyl derivátů hyaluronátu metodou DSC a TG

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dc.title Hodnocení stability n-alkyl derivátů hyaluronátu metodou DSC a TG cs
dc.title Stability evaluation of n-alkyl hyaluronic acid derivates by DSC and TG measurement en
dc.contributor.author Benešová, Karolína
dc.contributor.author Pekař, Miloslav
dc.contributor.author Lapčík Sr., Lubomír
dc.contributor.author Kučerík, Jiří
dc.relation.ispartof Journal of Thermal Analysis and Calorimetry
dc.identifier.issn 1388-6150 OCLC, Ulrich, Sherpa/RoMEO, JCR
dc.date.issued 2006
utb.relation.volume 83
utb.relation.issue 2
dc.citation.spage 341
dc.citation.epage 348
dc.type article
dc.language.iso en
dc.publisher Springer-Verlag en
dc.identifier.doi 10.1007/s10973-005-6870-x
dc.relation.uri http://www.scientific.net/MSF.514-516.1211
dc.subject DSC cs
dc.subject hyaluronová kyselina cs
dc.subject hyaluronát cs
dc.subject hydrofobizace cs
dc.subject indukční perioda cs
dc.subject TG cs
dc.subject DSC en
dc.subject hyaluronic acid en
dc.subject hydrophobization en
dc.subject induction period en
dc.subject TG en
dc.description.abstract Termické a termooxidační chování sodné soli kyseliny hyaluronové a jejich n-hexyl, n-tetradecyl a n-hexadecyl derivátů o stejném stupni substituce bylo studováno metodami DSC a DTG. Zjistila se snížená termická stabilita těchto derivátů oproti nesubstituovyným vzorkům, stejně jako nižší hodnoty termodynamicko-kinetických parametrů degradačních procesů. cs
dc.description.abstract The thermal and thermooxidative behavior of sodium salt of hyaluronic acid (HA) and its n-hexyl, n-decyl, n-tetradecyl and n-hexadecyl ether derivatives having an equal degree of substitution have been studied by means of differential scanning calorimetry (DSC) and thermogravimetry (TG). Derivatives were prepared by a substitution of H atom at the OH bound to the sixth C of N-acetyl-D-glucosamin of HA unit by n-hexyl, n-decyl, n-tetradecyl and n-hexadecyl chains. Both thermal and thermooxidative degradation of HA and derivatives resulted in multistep process. The main interest of this work was focused on processes occurring in the course of the first decomposition step. Experimental DSC data showed lower stability of derivatives and, remarkably lower heat evolution in comparison with original HA. On the other hand, TG measurement recorded lower mass loss for derivates which indicated appearance of new types of crosslinking reactions. Oxidative stability was evaluated by means of DSC that provided the induction period and the protection factor determination. Derivates showed remarkably lower stability in comparison with original HA en
dc.description.abstract comparing each other, the highest oxidation stability showed n-decyl and n-tetradecyl derivates. en
utb.faculty Faculty of Technology
dc.identifier.uri http://hdl.handle.net/10563/1000664
utb.identifier.rivid RIV/70883521:28110/06:63504722
utb.identifier.obdid 14555790
utb.identifier.scopus 2-s2.0-33644900256
utb.identifier.wok 000235902500013
utb.source j-riv
utb.contributor.internalauthor Lapčík Sr., Lubomír
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