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Cell response to PLA scaffolds functionalized with various seaweed polysaccharides

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dc.title Cell response to PLA scaffolds functionalized with various seaweed polysaccharides en
dc.contributor.author Özaltin, Kadir
dc.contributor.author Vargün, Elif
dc.contributor.author Di Martino, Antonio
dc.contributor.author Capáková, Zdenka
dc.contributor.author Lehocký, Marián
dc.contributor.author Humpolíček, Petr
dc.contributor.author Kazantseva, Natalia E.
dc.contributor.author Sáha, Petr
dc.relation.ispartof International Journal of Polymeric Materials and Polymeric Biomaterials
dc.identifier.issn 0091-4037 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2020
dc.type article
dc.language.iso en
dc.publisher Taylor and Francis Inc.
dc.identifier.doi 10.1080/00914037.2020.1798443
dc.relation.uri https://www.tandfonline.com/doi/abs/10.1080/00914037.2020.1798443?journalCode=gpom20
dc.subject polylactic acid en
dc.subject fucoidan en
dc.subject PLA scaffold en
dc.subject fibroblast cell en
dc.subject plasma treatment en
dc.description.abstract The porous polylactic acid matrix has been particularly developed as a scaffold in tissue engineering, drug loading, and wound dressing. However, the loading of active chemical compounds is challenging due to its highly hydrophobic nature and lack of functional groups for chemical bonding. Plasma treatment is a fast, heat and chemical-free solution to increase its hydrophilicity by oxidative functional groups and physical etching. In this study, a highly porous PLA scaffold was obtained by polyethylene glycol pore formation agent and treated by radiofrequency (RF) air plasma. Fucoidan from Fucus vesiculosus, Macrocystis pyrifera, and Undaria pinnatifida were used to immobilize onto the activated porous PLA surface for use as medicated wound dressings. The chemical composition and morphology were investigated by FTIR, SEM-EDS analysis, and cytocompatibility assay was studied mouse embryonic fibroblast cells (NIH/3T3). © 2020 Taylor & Francis Group, LLC. en
utb.faculty University Institute
dc.identifier.uri http://hdl.handle.net/10563/1009829
utb.identifier.obdid 43881887
utb.identifier.scopus 2-s2.0-85088833811
utb.identifier.wok 000553357500001
utb.identifier.coden IJPMC
utb.source j-scopus
dc.date.accessioned 2020-08-13T13:10:36Z
dc.date.available 2020-08-13T13:10:36Z
dc.description.sponsorship Ministry of Education, Youth and Sports of the Czech RepublicMinistry of Education, Youth & Sports - Czech Republic [LO1504]; Czech Science FoundationGrant Agency of the Czech Republic [19-16861S]
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Özaltin, Kadir
utb.contributor.internalauthor Vargün, Elif
utb.contributor.internalauthor Di Martino, Antonio
utb.contributor.internalauthor Capáková, Zdenka
utb.contributor.internalauthor Lehocký, Marián
utb.contributor.internalauthor Humpolíček, Petr
utb.contributor.internalauthor Kazantseva, Natalia E.
utb.contributor.internalauthor Sáha, Petr
utb.fulltext.affiliation Kadir Ozaltin a, Elif Vargun a,b, Antonio Di Martino a,c, Zdenka Capakova a, Marian Lehocky a, Petr Humpolicek a, Natalia Kazantseva a, Petr Saha a a Centre of Polymer Systems, Tomas Bata University in Zlín, Zlin, Czech Republic; b Faculty of Science, Chemistry Department, Mugla Sitki Kocman University, Mugla, Turkey; c Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, Russian Federation
utb.fulltext.dates Published online: 29 Jul 2020
utb.fulltext.sponsorship This work was supported by the Ministry of Education, Youth and Sports of the Czech Republic [Program NPU I, LO1504] and Czech Science Foundation [Grant no. 19-16861S].
utb.wos.affiliation [Ozaltin, Kadir; Vargun, Elif; Di Martino, Antonio; Capakova, Zdenka; Lehocky, Marian; Humpolicek, Petr; Kazantseva, Natalia; Saha, Petr] Tomas Bata Univ Zlin, Ctr Polymer Syst, Zlin, Czech Republic; [Vargun, Elif] Mugla Sitki Kocman Univ, Chem Dept, Fac Sci, Mugla, Turkey; [Di Martino, Antonio] Tomsk Polytech Univ, Res Sch Chem & Appl Biomed Sci, Tomsk, Russia
utb.scopus.affiliation Centre of Polymer Systems, Tomas Bata University in Zlín, Zlin, Czech Republic; Faculty of Science, Chemistry Department, Mugla Sitki Kocman University, Mugla, Turkey; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, Russian Federation
utb.fulltext.projects LO1504
utb.fulltext.projects 19-16861S
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Centre of Polymer Systems
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