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The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds

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dc.title The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds en
dc.contributor.author Rejmontová, Petra
dc.contributor.author Kovalčík, Adriána
dc.contributor.author Humpolíček, Petr
dc.contributor.author Capáková, Zdenka
dc.contributor.author Wrzecionko, Erik
dc.contributor.author Sáha, Petr
dc.relation.ispartof RSC Advances
dc.identifier.issn 2046-2069 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2019
utb.relation.volume 9
utb.relation.issue 22
dc.citation.spage 12346
dc.citation.epage 12353
dc.type article
dc.language.iso en
dc.publisher Royal Society of Chemistry
dc.identifier.doi 10.1039/c8ra09757g
dc.relation.uri https://pubs.rsc.org/en/content/articlelanding/2019/ra/c8ra09757g#!divAbstract
dc.description.abstract The mechanical properties of poly(vinyl alcohol) (PVA)-based scaffolds were successfully improved. The improvements in mechanical properties correlated with the amount of Kraft lignin in PVA matrices. The critical property for any scaffold is its capacity to allow cells to ingrow and survive within its internal structure. The ingrowth of cells was tested using bioreactors creating simulated in vivo conditions. In the context of all the mentioned parameters, the most advantageous properties were exhibited by the scaffold containing 99 wt% PVA and 1 wt% Kraft lignin. The composites with 1 wt% Kraft lignin exhibited sufficient mechanical stability, a lack of cytotoxicity, and mainly the ability to allow the ingrowth of cells into the scaffold in a rotation bioreactor. © 2019 The Royal Society of Chemistry. en
utb.faculty University Institute
utb.faculty Faculty of Technology
dc.identifier.uri http://hdl.handle.net/10563/1008659
utb.identifier.obdid 43880464
utb.identifier.scopus 2-s2.0-85065022175
utb.identifier.wok 000466758200021
utb.identifier.coden RSCAC
utb.source j-scopus
dc.date.accessioned 2019-07-08T12:00:01Z
dc.date.available 2019-07-08T12:00:01Z
dc.description.sponsorship Czech Science Foundation [17-05095S]; Ministry of Education, Youth and Sports of the Czech Republic (Program NPU I) [LO1504]; TBU in Zlin [IGA/CPS/2018/001]; Brno University of Technology internal project [FCH-S-18-5334]; project SoMoPro [6SA18032]; European Union; South Moravian Region [665860]
dc.rights Attribution-NonCommercial 3.0 International
dc.rights.uri http://creativecommons.org/licenses/by-nc/3.0/
dc.rights.access openAccess
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Rejmontová, Petra
utb.contributor.internalauthor Humpolíček, Petr
utb.contributor.internalauthor Capáková, Zdenka
utb.contributor.internalauthor Wrzecionko, Erik
utb.contributor.internalauthor Sáha, Petr
utb.fulltext.affiliation Petra Rejmontová a,b, Adriana Kovalcik c,d*, Petr Humpolíček a,b*, Zdenka Capáková a, Erik Wrzecionko a,e, Petr Sáha a,b a Centre of Polymer Systems, Tomas Bata University in Zlin, Trida Tomase Bati 5678, 76001 Zlin, Czech Republic. E-mail: humpolicek@utb.cz; Fax: +420-576-031-444; Tel: +420 576 038 035 b Polymer Centre, Faculty of Technology, Tomas Bata University in Zlin, Vavreckova 275, 760 01 Zlin, Czech Republic c Institute for Chemistry and Technology of Materials, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria d Department of Food Chemistry and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkynova 118, 612 00 Brno, Czech Republic. E-mail: adriana.kovalcik@gmail.com e Department of Physics and Materials Engineering, Tomas Bata University in Zlín, Vavrečkova 275, 760 01 Zlín, Czech Republic
utb.fulltext.dates Received 27th November 2018 Accepted 13th April 2019
utb.wos.affiliation [Rejmontova, Petra; Humpolicek, Petr; Capakova, Zdenka; Wrzecionko, Erik; Saha, Petr] Tomas Bata Univ Zlin, Ctr Polymer Syst, Trida Tomase Bati 5678, Zlin 76001, Czech Republic; [Rejmontova, Petra; Humpolicek, Petr; Saha, Petr] Tomas Bata Univ Zlin, Fac Technol, Polymer Ctr, Vavreckova 275, Zlin 76001, Czech Republic; [Kovalcik, Adriana] Graz Univ Technol, Inst Chem & Technol Mat, Stremayrgasse 9, A-8010 Graz, Austria; [Kovalcik, Adriana] Brno Univ Technol, Fac Chem, Dept Food Chem & Biotechnol, Purkynova 118, Brno 61200, Czech Republic; [Wrzecionko, Erik] Tomas Bata Univ Zlin, Dept Phys & Mat Engn, Vavreckova 275, Zlin 76001, Czech Republic
utb.scopus.affiliation Centre of Polymer Systems, Tomas Bata University in Zlin Trida Tomase Bati, Zlin, 76001, Czech Republic; Polymer Centre, Faculty of Technology, Tomas Bata University in Zlin, Vavreckova 275, Zlin, 760 01, Czech Republic; Institute for Chemistry and Technology of Materials, Graz University of Technology, Stremayrgasse 9, Graz, 8010, Austria; Department of Food Chemistry and Biotechnology, Faculty of Chemistry, Brno University of Technology, Purkynova 118, Brno, 612 00, Czech Republic; Department of Physics and Materials Engineering, Tomas Bata University in Zlín, Vavrečkova 275, Zlín, 760 01, Czech Republic
utb.fulltext.faculty Faculty of Technology
utb.fulltext.faculty Faculty of Technology
utb.fulltext.faculty Faculty of Technology
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Polymer Centre
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Polymer Centre
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Department of Physics and Materials Engineering
utb.fulltext.ou Centre of Polymer Systems
utb.fulltext.ou Polymer Centre
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