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Comparison of intracytoplasmic sperm injection and preselected intracytoplasmic sperm injection by time-lapse monitoring

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dc.title Comparison of intracytoplasmic sperm injection and preselected intracytoplasmic sperm injection by time-lapse monitoring en
dc.contributor.author Hlaváčová, Sylvie
dc.contributor.author Rumpíkova, Tat'ána
dc.contributor.author Rumpík, David
dc.contributor.author Lopatářová, Miloslava
dc.contributor.author Bělašková, Silvie
dc.contributor.author Feketeová, Lucia
dc.relation.ispartof Journal of Reproductive Medicine
dc.identifier.issn 0024-7758 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2019
utb.relation.volume 64
utb.relation.issue 3-4
dc.citation.spage 125
dc.citation.epage 130
dc.type article
dc.language.iso en
dc.publisher Science Printers and Publishers Inc.
dc.subject assisted reproductive techniques en
dc.subject human oocyte en
dc.subject hyaluronic acid en
dc.subject intracytoplasmic sperm injection en
dc.subject monitoring en
dc.subject sperm selection en
dc.description.abstract OBJECTIVE: To compare the methods of fertilization using intracytoplasmic sperm injection (ICSI) and preselected intracytoplasmic sperm injection (PICSI) via the assessment of time parameters during an early development of embryos by the timelapse monitoring system. STUDY DESIGN: In total, 258 embryos destined for embryo transfer by 136 couples undergoing in vitro fertilization (IVF) cycle with donated oocytes were evaluated retrospectively. The first patient group underwent the PICSI fertilization method and the second group the ICSI method. Exact time parameters of early embryo development were compared. RESULTS: The chance of clinical pregnancy is slightly decreased with the increasing time when the embryo has reached the 8-cell stage (p=0.017). Clinical pregnancy rate for the PICSI method was 54.9% and 50% for the ICSI method (odds ratio=1.216, 95% CI 0.611-2.42, p=0.065). By using the PICSI method there was a 22% greater chance of clinical pregnancy. This increase is not statistically significant. CONCLUSION: Our findings noted an important contribution of the PICSI method. We will continue to monitor the development of the pregnancy arising from this study, in order to contribute to a clarification whether the sperm bound to hyaluronic acid increases the chance of maintaining a pregnancy and carrying the fetus to term. en
utb.faculty Faculty of Applied Informatics
dc.identifier.uri http://hdl.handle.net/10563/1008603
utb.identifier.wok 000462002600009
utb.source j-wok
dc.date.accessioned 2019-07-08T11:59:58Z
dc.date.available 2019-07-08T11:59:58Z
utb.contributor.internalauthor Bělašková, Silvie
utb.wos.affiliation IVF Zlin Czech Republ, Clin Reprod Med & Gynaecol, Zlin, Czech Republic; UTB Zlin, Fac Appl Informat, Zlin, Czech Republic; Univ Vet & Pharmaceut Sci Brno, Brno, Czech Republic
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