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Functional outcome of low rectal resection evaluated by anorectal manometry

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dc.title Functional outcome of low rectal resection evaluated by anorectal manometry en
dc.contributor.author Ihnát, Peter
dc.contributor.author Vávra, Petr
dc.contributor.author Prokop, Jiří
dc.contributor.author Pelikán, Anton
dc.contributor.author Ihnát Rudinská, Lucia
dc.contributor.author Penka, Igor
dc.relation.ispartof ANZ Journal of Surgery
dc.identifier.issn 1445-1433 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2018
utb.relation.volume 88
utb.relation.issue 6
dc.citation.spage E512
dc.citation.epage E516
dc.type article
dc.language.iso en
dc.publisher Blackwell Publishing
dc.identifier.doi 10.1111/ans.14207
dc.relation.uri https://www.ncbi.nlm.nih.gov/pubmed/28922706
dc.subject anorectal manometry en
dc.subject bowel dysfunction en
dc.subject laparoscopy en
dc.subject low anterior resection syndrome en
dc.subject low anterior resection syndrome score en
dc.subject rectal cancer en
dc.description.abstract Background: Low anterior resection syndrome (LARS) covers disordered bowel function after rectal resection, leading to deterioration in patients’ quality of life. The aim of this study was to evaluate anorectal function after laparoscopic low anterior resection (LAR) by means of standardized instruments. Methods: This was a prospective clinical cohort study conducted in a single institution to assess functional outcome of patients 1 year after laparoscopic LAR by means of LARS score and high-resolution anorectal manometry. Results: In total, 65 patients were enrolled in the study. Mean tumour height was 9.4 ± 1.8 cm; total mesorectal excision during laparoscopic LAR with low end-to-end colorectal anastomosis was performed in all patients. One year after the surgery, minor LARS was detected in 33.9% of patients, major LARS in 36.9% of patients. Anorectal manometry revealed decreased resting pressure and normal squeeze pressure of the anal sphincters in the majority of our patients. Rectal compliance and rectal volume tolerability (first sensation, urge to defaecate and discomfort volume) were significantly reduced. The statistical testing of the correlation between LARS and manometry parameters showed that with increasing seriousness of LARS, values of some parameters (resting pressure, first sensation, urge to defaecate, discomfort volume and rectal compliance) were reduced. Conclusion: This study indicates that the majority of patients after laparoscopic LAR experience symptoms of minor or major LARS. These patients have decreased resting anal sphincter pressures, decreased rectal volume tolerability and decreased rectal compliance. © 2017 Royal Australasian College of Surgeons en
utb.faculty Faculty of Humanities
dc.identifier.uri http://hdl.handle.net/10563/1008059
utb.identifier.obdid 43877822
utb.identifier.scopus 2-s2.0-85048214977
utb.identifier.wok 000434214700007
utb.identifier.pubmed 28922706
utb.identifier.coden AJSNB
utb.source j-scopus
dc.date.accessioned 2018-07-27T08:47:42Z
dc.date.available 2018-07-27T08:47:42Z
utb.contributor.internalauthor Pelikán, Anton
utb.fulltext.affiliation Peter Ihnát *†, Petr Vávra *†, Jiří Prokop *†, Anton Pelikán *†‡, Lucia Ihnát Rudinská §, Igor Penka *† * Department of Surgical Studies, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic † Department of Surgery, University Hospital Ostrava, Ostrava, Czech Republic ‡ Faculty of Humanities, Tomas Bata University, Zlin, Czech Republic and § Department of Forensic Medicine, University Hospital Ostrava, Ostrava, Czech Republic
utb.fulltext.dates Accepted for publication 25 July 2017
utb.scopus.affiliation Department of Surgical Studies, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic; Department of Surgery, University Hospital Ostrava, Ostrava, Czech Republic; Faculty of Humanities, Tomas Bata University, Zlin, Czech Republic; Department of Forensic Medicine, University Hospital Ostrava, Ostrava, Czech Republic
utb.fulltext.faculty Faculty of Humanities
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