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Stimuli responsive and biomineralized scaffold: An implant for bone-tissue engineering

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dc.title Stimuli responsive and biomineralized scaffold: An implant for bone-tissue engineering en
dc.contributor.author Shah, Rushita
dc.contributor.author Saha, Nabanita
dc.contributor.author Zuckermann, Ronald N.
dc.contributor.author Sáha, Petr
dc.relation.ispartof Annual Technical Conference - ANTEC, Conference Proceedings
dc.identifier.isbn 9780985011277
dc.date.issued 2015
dc.citation.spage 2012
dc.citation.epage 2016
dc.event.title 73rd Annual Technical Conference and Exhibition of the Society of Plastics Engineers, SPE ANTEC Orlando 2015
dc.event.sdate 2015-03-23
dc.event.edate 2015-03-25
dc.type conferenceObject
dc.language.iso en
dc.publisher Society of Plastics Engineers
dc.relation.uri http://app.knovel.com/web/view/pdf/show.v/rcid:kp1W0PS002/cid:kt010QWJ61/viewerType:pdf/root_slug:antec-2015-proceedings/url_slug:stimuli-responsive-biomineralized
dc.relation.uri http://www.4spe.org/Resources/resource.aspx?ItemNumber=23166
dc.description.abstract Development of bioactive and stimuli responsive materials in the form of implant/scaffold is the urgent need that mimics the natural bone structure and function. To achieve such novel smart biomaterials "PVP-CMC-CaCO3" scaffold was prepared using PVP-CMC hydrogel as a matrix, following the biomimetic mineralization process i.e. simple liquid diffusion technique. The main concern of this study is to establish its stimuli responsive nature as it is one of the important factor of biomaterials. The swelling-deswelling capacity of "PVP-CMC-CaCO3" scaffold was carried out at 37°C using physiological solution. The morphological changes which occurred in the biomineralized scaffold during swellingdeswelling-reswelling and deswelling steps were confirmed using scanning electron microscopy. The obtained results concerning shape-size and thickness indicated that PVP-CMC-CaCO3, a hydrogel based scaffold is a true stimuli responsive biomaterial. en
utb.faculty University Institute
dc.identifier.uri http://hdl.handle.net/10563/1006965
utb.identifier.obdid 43877178
utb.identifier.scopus 2-s2.0-85010703399
utb.identifier.coden ACPED
utb.source d-scopus
dc.date.accessioned 2017-07-13T14:50:27Z
dc.date.available 2017-07-13T14:50:27Z
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Shah, Rushita
utb.contributor.internalauthor Saha, Nabanita
utb.contributor.internalauthor Sáha, Petr
utb.fulltext.affiliation Rushita Shah1, Nabanita Saha1*, Ronald N. Zuckermann2, Petr Saha1 1 Centre of Polymer Systems, University Institute, Tomas Bata University in Zlin, Nad Ovcirnou 3685, 760 01 Zlin, Czech Republic 2 Biological Nanostructures Facility, Molecular Foundry, Lawrence Berkeley Laboratory, 1 Cyclotron Road, Berkeley, California CA 94720, USA
utb.fulltext.dates -
utb.fulltext.references 1. M. Dessì, A. Borzacchiello, T.H.A Mohamed, I. Wafa, A. Fattah, L J. Ambrosio Biomed Mater Res Part A. 101A, 2984–2993 (2013). 2. L.H Lim, Y. Hwang, M. Kar. S. Varghese. Biomater. Sci. 2, 603–618, (2014). 3. D.S. Couto, Z. Hong, F. Mano, Acta Biomaterialia 5, 115–123 (2009). 4. N. Roy, Saha N, Kitano T, Saha P. J. Appl. Polym. Sci. 117, 1703-1710 (2010). 5. N. Saha, A. Saarai, N. Roy, T. Kitano, P. Saha: J. Biomater. Nanobiotechnol. 2, 85-90 (2011). 6. P. Saha, N. Saha, N. Roy: “Hydrogel Wound Covering” Patent no: 302405, Czech Republic 7. M.W.Rauch, M Dressler, H Scheel, D.V Opdenbosch, C Zollfrank. Eur. J. Inorg. Che. 5192-5198, (2012). 8. N. Saha, R. Shah, R. Vyroubal, T. Kitano, P. Saha: Novel Trends in Rheology V Book Series: AIP Conference Proceedings 1526, 292 – 300. ISSN: 0094-243X, ISBN: 978-073541151-7 (2013). 9. N. Saha, R. Vyroubal, R. Shah, T. Kitano, P. Saha: Novel Trends in Rheology V Book Series: AIP Conference Proceedings 1526 301-309, ISSN: 0094-243X, ISBN: 978-073541151-7, (2013). 10. R. Shah, N. Saha, T. Kitano, P. Saha. Journal of Applied polymer science. 131 (10) (2014) DOI: 10.1002/APP.40237. 11. M. Sadeghi, H. Hosseinzadeh. Brazilian Journal of Chemical Engineering, 30, 379-389, (2013) 12. Human Body Temperature http://en.wikipedia.org/wiki/Human_body_temperature (accessed on 28 September 2014) 13. Z.X Zhao, Z. Li ∗ , Q.B. Xia, E. Bajalis, H.X. Xi, Y.S. Lin. Chemical Engineering Journal 142, 263–270, (2008).
utb.fulltext.sponsorship The authors are thankful for the support of Research and Development for Innovation Operational Programme co-funded by the European Regional Development Fund (ERDF) and national budget of the Czech Republic within the framework of the Centre of Polymer Systems project (reg. number: CZ.1.05/2.1.00/03.0111), KONTAKT-II LH14050 (Czech-American Cooperation Project: 17140050302/2104). This work was also conducted within the framework of COST Action MP1301 “New Generation Biomimetic and Customized Implants for Bone Engineering” – www.cost.eu.
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