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Mineralized polymer composites as biogenic bone substitute material

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dc.title Mineralized polymer composites as biogenic bone substitute material en
dc.contributor.author Shah, Rushita
dc.contributor.author Saha, Nabanita
dc.contributor.author Kitano, Takeshi
dc.contributor.author Sáha, Petr
dc.relation.ispartof Proceedings of PPS-30: The 30th International Conference of the Polymer Processing Society
dc.identifier.issn 0094-243X Scopus Sources, Sherpa/RoMEO, JCR
dc.identifier.isbn 9780735413092
dc.date.issued 2015
utb.relation.volume 1664
dc.event.title 30th International Conference of the Polymer-Processing-Society (PPS)
dc.event.location Cleveland
utb.event.state-en United States
utb.event.state-cs Spojené státy americké
dc.event.sdate 2014-06-06
dc.event.edate 2014-06-12
dc.type conferenceObject
dc.language.iso en
dc.publisher American Institute of Physics (AIP)
dc.identifier.doi 10.1063/1.4918447
dc.relation.uri http://scitation.aip.org/content/aip/proceeding/aipcp/10.1063/1.4918447
dc.subject Adyanamic bone disorder en
dc.subject biomineralization en
dc.subject calcium carbonate en
dc.subject PVP-CMC hydrogel en
dc.subject polymer composite scaffold en
dc.description.abstract Mineralized polymer composites (MPC) are recognized as potential fillers of bone defects. Though bioceramics exhibits quite a good bone-bonding and vascularization, it is considered to be too stiff and brittle for using alone. Thus, the use of polymer scaffold instead of bioceramics has several advantages including combining the osteoconductivity and bone-bonding potential of the inorganic phase with the porosity and interconnectivity of the three-dimensional construction. Aiming the advantages of ceramic-polymer composite scaffolds, the calcium carbonate (CaCO3) based biomineralized scaffold was prepared, where the PVP-CMC hydrogel was used as an extracellular matrix. This paper is reported about the morphology, swelling trend (in physiological solution) and viscoelastic behavior of (90 min mineralized) MPC. The dry MPC are off-white, coarse in texture, comparatively less flexible than the original PVP-CMC based hydrogel film, and the deposition of granular structures on the surface of the hydrogel film confirms about the development of biomineralized scaffold/polymer composites. Irrespective of thickness, the dry MPC shows higher values of swelling ratio within 30 min, which varies between 200-250 approximately. The dynamic viscoelastic nature of freshly prepared MPC was investigated applying 1% and 10% strain. At higher strain the viscoelastic moduli (G' and G '') show significant change, and the nature of MPC turns from elastic to viscous. Based on the observed basic properties, the MPC (calcite based polymer composites) can be recommended for the treatment of adyanamic bone disorder. en
utb.faculty University Institute
utb.faculty Faculty of Technology
dc.identifier.uri http://hdl.handle.net/10563/1005811
utb.identifier.obdid 43873043
utb.identifier.scopus 2-s2.0-84984590211
utb.identifier.wok 000366584700065
utb.source d-wok
dc.date.accessioned 2016-04-12T11:51:59Z
dc.date.available 2016-04-12T11:51:59Z
dc.rights.access openAccess
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Shah, Rushita
utb.contributor.internalauthor Saha, Nabanita
utb.contributor.internalauthor Kitano, Takeshi
utb.contributor.internalauthor Sáha, Petr
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