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The chemical stability and cytotoxicity of carbonyl iron particles grafted with poly(glycidyl methacrylate) and the magnetorheological activity of their suspensions

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dc.title The chemical stability and cytotoxicity of carbonyl iron particles grafted with poly(glycidyl methacrylate) and the magnetorheological activity of their suspensions en
dc.contributor.author Cvek, Martin
dc.contributor.author Mrlík, Miroslav
dc.contributor.author Ilčíková, Markéta
dc.contributor.author Mosnáček, Jaroslav
dc.contributor.author Babayan, Vladimir Artur
dc.contributor.author Kuceková, Zdenka
dc.contributor.author Humpolíček, Petr
dc.contributor.author Pavlínek, Vladimír
dc.relation.ispartof RSC Advances
dc.identifier.issn 2046-2069 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2015
utb.relation.volume 5
utb.relation.issue 89
dc.citation.spage 72816
dc.citation.epage 72824
dc.type article
dc.language.iso en
dc.publisher Royal Society of Chemistry (RSC)
dc.identifier.doi 10.1039/c5ra11968e
dc.relation.uri http://pubs.rsc.org/en/Content/ArticleLanding/2015/RA/C5RA11968E#!divAbstract
dc.description.abstract Carbonyl iron (CI) particles were grafted with poly(glycidyl methacrylate) (PGMA) using atom transfer radical polymerization. Compact coating of PGMA largely improved the chemical stability of the particles in an acid environment and thus reduced the common drawback of bare CI particles. Furthermore, due to possible medical applications of CI-polymer systems for magnetic drug targeting, an in vitro cytotoxicity test was performed using an NIH/3T3 cell line. The cell viability was evaluated by spectrometric assay (MTT). The results show that the prepared particles are not cytotoxic. Moreover, bare CI particles as well as synthesized core-shell particles were suspended in silicone oil, and the rheological behavior of MR suspensions was investigated in controlled shear rate mode under various magnetic field strengths. Dynamic yield stress as a measure of the rigidity of the created internal structures of the suspensions was determined using the Herschel-Bulkley model, which provided a reasonably good fit for rheological data. MR suspensions of PGMA-coated particles exhibited only slightly decreased yield stresses due to their negligibly-affected magnetic performance. This journal is © The Royal Society of Chemistry. en
utb.faculty University Institute
utb.faculty Faculty of Technology
dc.identifier.uri http://hdl.handle.net/10563/1005641
utb.identifier.rivid RIV/70883521:28610/15:43873186!RIV16-MSM-28610___
utb.identifier.obdid 43873617
utb.identifier.scopus 2-s2.0-84940854775
utb.identifier.wok 000360552000045
utb.identifier.coden RSCAC
utb.source j-scopus
dc.date.accessioned 2015-10-02T15:10:13Z
dc.date.available 2015-10-02T15:10:13Z
dc.description.sponsorship Operational Program Research and Development for Innovations - European Regional Development Fund (ERDF); National Budget of the Czech Republic [CZ.1.05/2.1.00/03.0111]; TBU in Zlin [IGA/CPS/2015/007]; Centre of Excellence FUN-MAT; Czech Science Foundation [13-08944S]
dc.rights Attribution-NonCommercial 4.0 International
dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.access openAccess
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Cvek, Martin
utb.contributor.internalauthor Mrlík, Miroslav
utb.contributor.internalauthor Babayan, Vladimir Artur
utb.contributor.internalauthor Kuceková, Zdenka
utb.contributor.internalauthor Humpolíček, Petr
utb.contributor.internalauthor Pavlínek, Vladimír
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