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Relaxation of microparticles exposed to hydrodynamic forces in microfluidic conduits

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dc.title Relaxation of microparticles exposed to hydrodynamic forces in microfluidic conduits en
dc.contributor.author Janča, Josef
dc.contributor.author Halabalová, Věra
dc.contributor.author Polášek, Vladimír
dc.contributor.author Vašina, Martin
dc.contributor.author Menshikova, Anastasia
dc.relation.ispartof Analytical and Bioanalytical Chemistry
dc.identifier.issn 1618-2642 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2011-02
utb.relation.volume 399
utb.relation.issue 4
dc.citation.spage 1481
dc.citation.epage 1491
dc.type article
dc.language.iso en
dc.publisher Springer Heidelberg en
dc.identifier.doi 10.1007/s00216-010-4163-0
dc.relation.uri http://www.springerlink.com/content/57k8125478805k15/
dc.subject Microthermal field-flow fractionation en
dc.subject Focusing mechanism en
dc.subject Relaxation en
dc.subject Microfluidic separations en
dc.subject Micrometer-sized particles en
dc.subject Theoretical model and experiments at low Reynolds numbers en
dc.description.abstract The behavior of microparticles exposed to gravitational and lift forces and to the velocity gradient in flow velocity profile formed in microfluidic conduits is studied from the viewpoint of the transient period (the relaxation) between the moment at which a particle starts to be transported by the hydrodynamic flow and the time at which it reaches an equilibrium position, characterized by a balance of all active forces. The theoretical model allowing the calculation of the relaxation time is proposed. The numerical calculus based on the proposed model is compared with the experimental data obtained under different experimental conditions, namely, for different lengths of microfluidic channels, different average linear velocities of the carrier liquid, and different sizes and densities of the particles used in the study. The results are important for the optimization of microfluidic separation units such as microthermal field-flow fractionation channels in which the separation or manipulation of the microparticles of various origin, synthetic, natural, biological, etc., is performed under similar experimental conditions but by applying an additional thermodynamic force. en
utb.faculty Faculty of Technology
utb.faculty Faculty of Applied Informatics
dc.identifier.uri http://hdl.handle.net/10563/1002162
utb.identifier.rivid RIV/70883521:28110/11:00000898!RIV12-MSM-28110___
utb.identifier.rivid RIV/70883521:28140/11:00000898!RIV12-MSM-28140___
utb.identifier.obdid 43865038
utb.identifier.scopus 2-s2.0-79451471188
utb.identifier.wok 000286599200010
utb.identifier.pubmed 20835866
utb.identifier.coden ABCNB
utb.source j-wok
dc.date.accessioned 2011-08-16T15:06:35Z
dc.date.available 2011-08-16T15:06:35Z
utb.contributor.internalauthor Janča, Josef
utb.contributor.internalauthor Halabalová, Věra
utb.contributor.internalauthor Polášek, Vladimír
utb.contributor.internalauthor Vašina, Martin
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