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Polysaccharides Coatings on Medical-Grade PVC: A Probe into Surface Characteristics and the Extent of Bacterial Adhesion

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dc.title Polysaccharides Coatings on Medical-Grade PVC: A Probe into Surface Characteristics and the Extent of Bacterial Adhesion en
dc.contributor.author Asadinezhad, Ahmad
dc.contributor.author Novák, Igor
dc.contributor.author Lehocký, Marián
dc.contributor.author Bílek, František
dc.contributor.author Veselá, Alenka
dc.contributor.author Junkar, Ita
dc.contributor.author Sáha, Petr
dc.contributor.author Popelka, Antonín
dc.relation.ispartof Molecules
dc.identifier.issn 1420-3049 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2010
utb.relation.volume 15
utb.relation.issue 2
dc.citation.spage 1007
dc.citation.epage 1027
dc.type article
dc.language.iso en
dc.publisher Molecular Diversity Preservation International (MDPI) en
dc.identifier.doi 10.3390/molecules15021007
dc.relation.uri http://www.mdpi.com/1420-3049/15/2/1007/
dc.subject antibacterial compound en
dc.subject polysaccharide en
dc.subject polyvinyl chloride en
dc.subject chitosan en
dc.subject pectin en
dc.subject plasma glow-discharge en
dc.subject antibacterial activity en
dc.subject poly(vinyl chloride) en
dc.subject antimicrobial activity en
dc.subject ozone-treatment en
dc.subject polyester en
dc.subject oxygen en
dc.subject chemistry en
dc.subject nonwoven en
dc.description.abstract Medical-grade polyvinyl chloride was coated by polysaccharides through a novel physicochemical approach. An initial surface activation was performed foremost via diffuse coplanar surface barrier discharge plasma in air at ambient temperature and pressure. Then, radical graft copolymerization of acrylic acid through grafting-from pathway was directed to render a well-defined brush of high density, and finally a chitosan monolayer and chitosan/pectin alternating multilayer were bound onto the functionalized surfaces. Surface characteristics were systematically investigated using several probe techniques. In vitro bacterial adhesion and biofilm formation assays indicated that a single chitosan layer was incapable of hindering the adhesion of a Staphylococcus aureus bacterial strain, while up to 30% reduction was achieved by the chitosan/pectin layered assembly. On the other hand, chitosan and chitosan/pectin multilayer could retard Escherichia coli adhesion by 50% and 20%, respectively. Furthermore, plasma treated and graft copolymerized samples were also found effective to diminish the degree of adherence of Escherichia coli. en
utb.faculty University Institute
dc.identifier.uri http://hdl.handle.net/10563/1001714
utb.identifier.rivid RIV/70883521:28610/10:63509221!RIV11-MPO-28610___
utb.identifier.obdid 43864574
utb.identifier.scopus 2-s2.0-77649225101
utb.identifier.wok 000274929200030
utb.source j-riv
dc.rights Attribution-NonCommercial-NoDerivs 3.0 Unported
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/
dc.rights.access openAccess
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Asadinezhad, Ahmad
utb.contributor.internalauthor Lehocký, Marián
utb.contributor.internalauthor Sáha, Petr
utb.contributor.internalauthor Bílek, František
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