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An in vitro bacterial adhesion assessment of surface-modified medical-grade PVC

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dc.title An in vitro bacterial adhesion assessment of surface-modified medical-grade PVC en
dc.contributor.author Asadinezhad, Ahmad
dc.contributor.author Novák, Igor
dc.contributor.author Lehocký, Marián
dc.contributor.author Sedlařík, Vladimír
dc.contributor.author Vesel, Alenka
dc.contributor.author Junkar, Ita
dc.contributor.author Sáha, Petr
dc.contributor.author Chodák, Ivan
dc.relation.ispartof Colloids and Surfaces B: Biointerfaces
dc.identifier.issn 0927-7765 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2010
utb.relation.volume 77
utb.relation.issue 2
dc.citation.spage 246
dc.citation.epage 256
dc.type article
dc.language.iso en
dc.publisher Elsevier Science B.V. en
dc.identifier.doi 10.1016/j.colsurfb.2010.02.006
dc.relation.uri https://www.sciencedirect.com/science/article/pii/S0927776510000809
dc.subject bacterial adhesion en
dc.subject plasma treatment en
dc.subject polyvinylchloride en
dc.subject surface modification en
dc.subject plasma glow-discharge en
dc.subject antibacterial activity en
dc.subject poly(vinyl chloride) en
dc.subject polymer surfaces en
dc.subject nitrogen-plasma en
dc.subject ozone-treatment en
dc.subject chitosan en
dc.subject oxygen en
dc.subject chlorhexidine en
dc.subject films en
dc.description.abstract Medical-grade polyvinyl chloride was surface modified by a multistep physicochemical approach to improve bacterial adhesion prevention properties. This was fulfilled via surface activation by diffuse coplanar surface barrier discharge plasma followed by radical graft copolymerization of acrylic acid through surface-initiated pathway to render a structured high density brush. Three known antibacterial agents, bronopol, benzalkonium chloride, and chlorhexidine, were then individually coated onto functionalized surface to induce biological properties. Various modern surface probe techniques were employed to explore the effects of the modification steps. In vitro bacterial adhesion and biofilm formation assay was performed. Escherichia coli strain was found to be more susceptible to modifications rather than Staphylococcus aureus as up to 85% reduction in adherence degree of the former was observed upon treating with above antibacterial agents, while only chlorhexidine could retard the adhesion of the latter by 50%. Also, plasma treated and graft copolymerized samples were remarkably effective to diminish the adherence of E. coli. (C) 2010 Elsevier B.V. All rights reserved. en
utb.faculty University Institute
dc.identifier.uri http://hdl.handle.net/10563/1001713
utb.identifier.rivid RIV/70883521:28610/10:63509220!RIV11-MPO-28610___
utb.identifier.obdid 43864573
utb.identifier.scopus 2-s2.0-77950858355
utb.identifier.wok 000276753600018
utb.source j-riv
dc.rights.access openAccess
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Asadinezhad, Ahmad
utb.contributor.internalauthor Lehocký, Marián
utb.contributor.internalauthor Sedlařík, Vladimír
utb.contributor.internalauthor Sáha, Petr
utb.fulltext.affiliation Ahmad Asadinezhad3, Igor Novákb, Marián Lehockýc’*, Vladimir Sedlařík3, Alenka Veseld, ItaJunkard, Petr Sáhaa, Ivan Chodák0
utb.fulltext.dates -
utb.fulltext.sponsorship Financing this research by the Ministry of Education, Youth, and Sports of the Czech Republic (Grant VZ MSM 7088352101) as well as Ministry of Industry and Trade of the Czech Republic (Grant MPO 2A-1TP1/126), the Slovak Academy of Sciences (Grant VEGA 2/7103/27), and the Slovenia Ministry of Higher Education, Science, and Technology (Program P2-0082-2, Thin Film Structures and Plasma Surface Engineering) is appreciated.
utb.fulltext.projects MSM 7088352101
utb.fulltext.projects MPO 2A-1TP1/126
utb.fulltext.projects VEGA 2/7103/27
utb.fulltext.faculty -
utb.fulltext.ou -
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