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Stimuli-responsive thin film composites of conducting polymers and cellulose nanocrystals for tissue engineering

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dc.title Stimuli-responsive thin film composites of conducting polymers and cellulose nanocrystals for tissue engineering en
dc.contributor.author Korábková, Eva
dc.contributor.author Boeva, Zhanna
dc.contributor.author Radaszkiewicz, Katarzyna Anna
dc.contributor.author Skopalová, Kateřina
dc.contributor.author Kašpárková, Věra
dc.contributor.author Xu, Wenyang
dc.contributor.author Wang, Xiaoju
dc.contributor.author Pacherník, Jiří
dc.contributor.author Minařík, Antonín
dc.contributor.author Lindfors, Tom
dc.contributor.author Humpolíček, Petr
dc.relation.ispartof International Journal of Biological Macromolecules
dc.identifier.issn 0141-8130 Scopus Sources, Sherpa/RoMEO, JCR
dc.identifier.issn 1879-0003 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2024
utb.relation.volume 265
dc.type article
dc.language.iso en
dc.publisher Elsevier B.V.
dc.identifier.doi 10.1016/j.ijbiomac.2024.131036
dc.relation.uri Stimuli-responsive thin film composites of conducting polymers and cellulose nanocrystals for tissue engineering
dc.relation.uri https://www.sciencedirect.com/science/article/pii/S0141813024018415/pdfft?md5=e24a9586223cca3b164826a0bf2b47da&pid=1-s2.0-S0141813024018415-main.pdf
dc.subject cellulose nanocrystals en
dc.subject polypyrrole en
dc.subject poly(3,4-ethylenedioxythiophene) en
dc.subject human induced pluripotent stem cells en
dc.description.abstract Thin composite films comprising two primary representatives of conducting polymers, poly(3, 4-ethylenedioxythiophene) (PEDOT) and polypyrrole (PPy), with eco-friendly cellulose nanocrystals (CNC) were prepared through electrochemical polymerization. The combination of CNC and PEDOT (or PPy) results in the formation of films with highly different surface topography and thickness. Intriguingly, different surface conductivity of PEDOT and PPy was revealed by atomic force microscopy albeit that the electrochemical properties were rather similar. The biological properties of the composites in contact with prospective human induced pluripotent stem cells (hiPSC) and cardiomyocytes derived from hiPSC demonstrated good cytocompatibility of both composites and their potential in engineering of electro-sensitive tissues. The as-prepared conducting, eco-friendly and cytocompatible composites are thus promising candidates for biomedical applications where stimuli-responsivity is a crucial cell-instructive property. en
utb.faculty University Institute
utb.faculty Faculty of Technology
utb.faculty Faculty of Technology
dc.identifier.uri http://hdl.handle.net/10563/1011972
utb.identifier.scopus 2-s2.0-85189022293
utb.identifier.wok 001223225900001
utb.identifier.pubmed 38518940
utb.identifier.coden IJBMD
utb.source j-scopus
dc.date.accessioned 2024-04-17T13:13:07Z
dc.date.available 2024-04-17T13:13:07Z
dc.description.sponsorship Jane ja Aatos Erkon Säätiö, J&AE; Ministerstvo Školství, Mládeže a Tělovýchovy, MŠMT; Grantová Agentura České Republiky, GA ČR, (23-07425S); DKRVO, (RP/CPS/2022/001)
dc.description.sponsorship Czech Science Foundation [23-07425S]; Ministry of Education, Youth and Sports of the Czech Republic - DKRVO [RP/CPS/2022/001]; Jane and Aatos Erkko Foundation
utb.ou Centre of Polymer Systems
utb.ou Department of Fat, Surfactant and Cosmetics Technology
utb.ou Department of Physics and Materials Engineering
utb.contributor.internalauthor Korábková, Eva
utb.contributor.internalauthor Skopalová, Kateřina
utb.contributor.internalauthor Kašpárková, Věra
utb.contributor.internalauthor Minařík, Antonín
utb.contributor.internalauthor Humpolíček, Petr
utb.fulltext.sponsorship Authors PH, VK, KS, AM and JP acknowledge the support by the Czech Science Foundation (23-07425S). The project of Ministry of Education, Youth and Sports of the Czech Republic – DKRVO (RP/CPS/2022/001) is also acknowledged. WX appreciates the funding from the Jane and Aatos Erkko Foundation (Project: Healing the wounds with Finnish woods).
utb.wos.affiliation [Korabkova, Eva; Skopalova, Katerina; Kasparkova, Vera; Minarik, Antonin; Humpolicek, Petr] Tomas Bata Univ Zlin, Ctr Polymer Syst, nam T G Masaryka 5555, Zlin 76001, Czech Republic; [Boeva, Zhanna; Lindfors, Tom] Abo Akad Univ, Fac Sci & Engn, Lab Mol Sci & Engn, Henriksgatan 2, Turku 20500, Abo, Finland; [Radaszkiewicz, Katarzyna Anna; Pachernik, Jiri] Masaryk Univ, Fac Sci, Brno 62500, Czech Republic; [Kasparkova, Vera] Tomas Bata Univ Zlin, Fac Technol, Dept Fat Surfactant & Cosmet Technol, nam T G Masaryka 5555, Zlin 76001, Czech Republic; [Xu, Wenyang; Wang, Xiaoju] Abo Akad Univ, Fac Sci & Engn, Lab Nat Mat Technol, Henriksgatan 2, Turku 20500, Abo, Finland; [Minarik, Antonin] Tomas Bata Univ Zlin, Fac Technol, Dept Phys & Mat Engn, Vavreckova 275, Zlin 76001, Czech Republic
utb.scopus.affiliation Centre of Polymer Systems, Tomas Bata University in Zlín, nám. T. G. Masaryka 5555, Zlín, 760 01, Czech Republic; Åbo Akademi University, Faculty of Science and Engineering, Laboratory of Molecular Science and Engineering, Henriksgatan 2, Turku, 20500, Åbo, Finland; Masaryk University, Faculty of Science, Brno, 625 00, Czech Republic; Department of Fat, Surfactant and Cosmetics Technology, Faculty of Technology, Tomas Bata University in Zlín, nám. T. G. Masaryka 5555, Zlín, 760 01, Czech Republic; Åbo Akademi University, Faculty of Science and Engineering, Laboratory of Natural Materials Technology, Henriksgatan 2, Turku, 20500, Åbo, Finland; Department of Physics and Materials Engineering, Faculty of Technology, Tomas Bata University in Zlin, Vavrečkova 275, Zlin, 760 01, Czech Republic
utb.fulltext.projects 23-07425S
utb.fulltext.projects DKRVO (RP/CPS/2022/001)
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