Synthesis of 2-thioxo-imidazolines via reaction of 1-unsubstituted 3-aminoquinoline-2,4-diones with isothiocyanates

Prucková, Zdeňka; Klásek, Antonín; Mikšík, I.; Růžička, A.; Lyčka, Antonín

dc.title	Synthesis of 2-thioxo-imidazolines via reaction of 1-unsubstituted 3-aminoquinoline-2,4-diones with isothiocyanates	en
dc.contributor.author	Prucková, Zdeňka
dc.contributor.author	Klásek, Antonín
dc.contributor.author	Mikšík, I.
dc.contributor.author	Růžička, A.
dc.contributor.author	Lyčka, Antonín
dc.relation.ispartof	Tetrahedron
dc.identifier.issn	0040-4020 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued	2009
utb.relation.volume	65
utb.relation.issue	45
dc.citation.spage	9103
dc.citation.epage	9115
dc.type	article
dc.language.iso	en
dc.publisher	Pergamon Elsevier Science Ltd.	en
dc.identifier.doi	10.1016/j.tet.2009.09.048
dc.relation.uri	https://www.sciencedirect.com/science/article/pii/S0040402009013969
dc.subject	1	en
dc.subject	3-Diphenylureas	en
dc.subject	Rearrangement	en
dc.subject	Thiones	en
dc.subject	Thiourea derivatives	en
dc.subject	α-Aminoketones	en
dc.description.abstract	3-Alkyl/Aryl-3-aminochinoline-2,4-diony reagují s isothiokyanáty za tvorby 3a-alkyl/aryl-1,2,3,3a-tetrahydro-9b-hydroxy-2-thioxo-5H-imidazo-[4,5-c]chinolin-4(9bH)-onů. Tyto sloučeniny přesmykují v kyselém prostředí na nové 4-(2-aminofenyl)-1H-imidazol-2(3H)-thiony a 1,3-bis(2-(2,3-dihydro-2-thioxo-1H-imidazol-5-yl)fenyl)močoviny.	cs
dc.description.abstract	3-Alkyl/Aryl-3-aminoquinoline-2,4-diones react with isothiocyanates to give 3a-alkyl/aryl-1,2,3,3a-tetrahydro-9b-hydroxy-2-thioxo-5H-imidazo-[4,5-c]quinolin-4(9bH)-ones. These compounds rearrange in an acidit environment to give novel 4-(2-aminophenyl)-1H-imidazole-2(3H)-thiones and 1,3-bis(2-(2,3-dihydro-2-thioxo-1H-imidazol-5-yl)phenyl)ureas.	en
utb.faculty	Faculty of Technology
dc.identifier.uri	http://hdl.handle.net/10563/1000992
utb.identifier.rivid	RIV/70883521:28110/09:63508078!RIV10-MSM-28110___
utb.identifier.obdid	43860114
utb.identifier.scopus	2-s2.0-70349778613
utb.identifier.wok	000271094000007
utb.source	j-riv
utb.contributor.internalauthor	Prucková, Zdeňka
utb.contributor.internalauthor	Klásek, Antonín
utb.scopus.affiliation	Prucková Z., Department of Chemistry, Faculty of Technology, Tomas Bata University, 762 72 Zlín, Czech Republic; Klásek A., Department of Chemistry, Faculty of Technology, Tomas Bata University, 762 72 Zlín, Czech Republic; Lyčka A., Research Institute for Organic Syntheses (VUOS), 533 54 Pardubice 20, Rybitví 296, Czech Republic, University of Hradec Králové, Faculty of Education, CZ 500 03 Hradec Kralove 3, Rokitanského 62, Czech Republic; Mikšík I., University of Hradec Králové, Faculty of Education, CZ 500 03 Hradec Kralove 3, Rokitanského 62, Czech Republic, Department of Physiology, Academy of Sciences of the Czech Republic, 142 20 Prague, Czech Republic; Růžička A., Department of General and Inorganic Chemistry, Faculty of Chemical Technology, University of Pardubice, 53210 Pardubice, Czech Republic