Reaction of 1-substituted 3-aminoquinoline-2,4-diones with isothiocyanates. An easy pathway to generate novel 2-thioxo-10H-spiro[imidazoline-5,3-indole]-2,2´-diones.

Abstract

3-Butyl-3-aminochinolin-2,4-diony reagují s isothiokyanáty za tvorby nových 3a-butyl-9b-hydroxy-hexahydro-imidazo[4,5-c]chinolin-2-onů. Tyto sloučeniny přesmykují v kyselém prostředí a poskytují (E)- a/nebo (Z)-4-butyliden-2-thioxo-1´H-spiro[imidazolin-5,3´-indol]-2,2-diony.

3-Butyl-3-aminoquinoline-2,4-diones react with isothiocyanates to give novel 3a-butyl-9b-hydroxy-hexahydro-imidazo[4,5-c]quinolin-2-ones . These compounds rearrange in an acidit environment to give (E)- and/or (Z)-4-butylidene-2-thioxo-1´H-spiro[imidazoline-5,3´-indole]-2,2-diones.