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Biocompatible and antibacterial gelatin-based polypyrrole cryogels

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dc.title Biocompatible and antibacterial gelatin-based polypyrrole cryogels en
dc.contributor.author Milakin, Konstantin A.
dc.contributor.author Capáková, Zdenka
dc.contributor.author Acharya, Udit
dc.contributor.author Vajďák, Jan
dc.contributor.author Morávková, Zuzana
dc.contributor.author Hodan, Jiří
dc.contributor.author Humpolíček, Petr
dc.contributor.author Bober, Patrycja
dc.relation.ispartof Polymer
dc.identifier.issn 0032-3861 Scopus Sources, Sherpa/RoMEO, JCR
dc.date.issued 2020
utb.relation.volume 197
dc.type article
dc.language.iso en
dc.publisher Elsevier Ltd
dc.identifier.doi 10.1016/j.polymer.2020.122491
dc.relation.uri https://www.sciencedirect.com/science/article/pii/S0032386120303232
dc.subject Polypyrrole en
dc.subject Gelatin en
dc.subject Cryogels en
dc.subject Conductivity en
dc.subject Cytotoxicity en
dc.subject Antibacterial properties en
dc.description.abstract Polypyrrole-gelatin cryogels were synthesized by oxidative cryopolymerization of pyrrole in the presence of gelatin. Vibrational spectroscopy confirmed formation of doped polypyrrole. Mechanical and pore structure stability of the resulting macroporous materials (pore size 10–50 μm) was shown to increase with increasing of gelatin content in initial polymerization medium, reaching plateau at 6 wt%. Thermal stability of polypyrrole-gelatin cryogels was found to be enhanced in comparison to its individual components. Electrical conductivity of all prepared cryogels (2–5 S cm−1) was similar to that of conventional polypyrrole. Cytotoxicity of polypyrrole-gelatin cryogels was found to decrease with increasing of gelatin concentration in the initial reaction mixture. The cryogel obtained using 8 wt% of gelatin showed the lowest cytotoxic effect reaching only mild cytotoxicity at 100% extract concentration. Polypyrrole-gelatin gels showed significant level of antibacterial activity without additional antibacterial agents. © 2020 Elsevier Ltd en
utb.faculty University Institute
dc.identifier.uri http://hdl.handle.net/10563/1009665
utb.identifier.scopus 2-s2.0-85083761680
utb.identifier.wok 000533634800007
utb.identifier.coden POLMA
utb.source j-scopus
dc.date.accessioned 2020-05-06T19:41:53Z
dc.date.available 2020-05-06T19:41:53Z
dc.description.sponsorship Czech Science FoundationGrant Agency of the Czech Republic [18-04669S, 19-16861S]; TBU in Zlin [IGA/CPS/2019/001]
utb.ou Centre of Polymer Systems
utb.contributor.internalauthor Capáková, Zdenka
utb.contributor.internalauthor Vajďák, Jan
utb.contributor.internalauthor Humpolíček, Petr
utb.fulltext.sponsorship The authors wish to thank the Czech Science Foundation , authors K. A. Milakin, U. Acharya and P. Bober the grant No. 18-04669S , authors P. Humpolíček and Z. Capáková the grant No. 19-16861S . J. Vajďák gratefully acknowledges support from the internal grant IGA/CPS/2019/001 of TBU in Zlin, financed from funds for specific academic research. The authors are grateful to Maria A. Milakina for her help with graphical abstract.
utb.wos.affiliation [Milakin, Konstantin A.; Acharya, Udit; Moravkova, Zuzana; Hodan, Jiri; Bober, Patrycja] Acad Sci Czech Republ, Inst Macromol Chem, Prague 16206 6, Czech Republic; [Capakova, Zdenka; Vajdak, Jan; Humpolicek, Petr] Tomas Bata Univ Zlin, Ctr Polymer Syst, Zlin 76001, Czech Republic; [Capakova, Zdenka; Vajdak, Jan; Humpolicek, Petr] Tomas Bata Univ Zlin, Fac Technol, Zlin 76001, Czech Republic
utb.scopus.affiliation Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Prague 6, 162 06, Czech Republic; Centre of Polymer Systems and Faculty of Technology, Tomas Bata University in Zlin, Zlin, 760 01, Czech Republic
utb.fulltext.projects 18-04669S
utb.fulltext.projects 19-16861S
utb.fulltext.projects IGA/CPS/2019/001
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